Piracetam and dyslexia: Effects on reading tests

Colin R. Wilsher, David Bennett, Christopher H. Chase, C. Keith Conners, Mark DiIanni, Lynne Feagans, Leo J. Hanvik, Elayne Helfgott, Harold Koplewicz, Philip Overby, Mark Reader, Rita G. Rudel, Paula Tallal

Research output: Contribution to journalArticle

Abstract

Previous research has suggested that dyslexics treated with piracetam have shown improvements in reading skills, verbal memory and verbal conceptualizing ability, feature analysis, and processing of letter-like stimuli. Two hundred twenty-five dyslexic children between the ages of 7 years 6 months and 12 years 11 months whose reading skills were significantly below their intellectual capacity were enrolled in a multicenter, 36-week, double-blind, placebo-controlled study. Children of below average intelligence, with abnormal findings on audiologic, ophthalmologic, neurologic, psychiatric, and physical examinations, who were emotionally disturbed or educationally deprived and who had recently been treated with psychoactive medication were excluded from the trial. Piracetam was well tolerated, with no serious adverse clinical or laboratory effects reported. Piracetam-treated children showed significant improvements in reading ability (Gray Oral Reading Test) and reading comprehension (Gilmore Oral Reading Test). Treatment effects were evident after 12 weeks and were sustained for the total period (36 weeks).

Original languageEnglish (US)
Pages (from-to)230-237
Number of pages8
JournalJournal of clinical psychopharmacology
Volume7
Issue number4
StatePublished - Jan 1 1987
Externally publishedYes

Fingerprint

Piracetam
Dyslexia
Reading
Aptitude
Neurologic Examination
Intelligence
Physical Examination
Psychiatry
Placebos
Research

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)

Cite this

Wilsher, C. R., Bennett, D., Chase, C. H., Conners, C. K., DiIanni, M., Feagans, L., ... Tallal, P. (1987). Piracetam and dyslexia: Effects on reading tests. Journal of clinical psychopharmacology, 7(4), 230-237.

Piracetam and dyslexia : Effects on reading tests. / Wilsher, Colin R.; Bennett, David; Chase, Christopher H.; Conners, C. Keith; DiIanni, Mark; Feagans, Lynne; Hanvik, Leo J.; Helfgott, Elayne; Koplewicz, Harold; Overby, Philip; Reader, Mark; Rudel, Rita G.; Tallal, Paula.

In: Journal of clinical psychopharmacology, Vol. 7, No. 4, 01.01.1987, p. 230-237.

Research output: Contribution to journalArticle

Wilsher, CR, Bennett, D, Chase, CH, Conners, CK, DiIanni, M, Feagans, L, Hanvik, LJ, Helfgott, E, Koplewicz, H, Overby, P, Reader, M, Rudel, RG & Tallal, P 1987, 'Piracetam and dyslexia: Effects on reading tests', Journal of clinical psychopharmacology, vol. 7, no. 4, pp. 230-237.
Wilsher CR, Bennett D, Chase CH, Conners CK, DiIanni M, Feagans L et al. Piracetam and dyslexia: Effects on reading tests. Journal of clinical psychopharmacology. 1987 Jan 1;7(4):230-237.
Wilsher, Colin R. ; Bennett, David ; Chase, Christopher H. ; Conners, C. Keith ; DiIanni, Mark ; Feagans, Lynne ; Hanvik, Leo J. ; Helfgott, Elayne ; Koplewicz, Harold ; Overby, Philip ; Reader, Mark ; Rudel, Rita G. ; Tallal, Paula. / Piracetam and dyslexia : Effects on reading tests. In: Journal of clinical psychopharmacology. 1987 ; Vol. 7, No. 4. pp. 230-237.
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