Pilomyxoid astrocytoma: a review.

Ricardo J. Komotar; J. Mocco; Benjamin S. Carson; Michael E. Sughrue; Brad E. Zacharia; Alexander C. Sisti; Peter D. Canoll; Alexander G. Khandji; Tarik Tihan; Peter C. Burger; Jeffery N. Bruce

Pilomyxoid astrocytoma: a review.

Ricardo J. Komotar, J. Mocco, Benjamin S. Carson, Michael E. Sughrue, Brad E. Zacharia, Alexander C. Sisti, Peter D. Canoll, Alexander G. Khandji, Tarik Tihan, Peter C. Burger, Jeffery N. Bruce

Research output: Contribution to journal › Review article › peer-review

45 Scopus citations

Abstract

Pilomyxoid astrocytoma (PMA) is a recently described type of brain tumor. PMA shares similar features with pilocytic astrocytoma (PA), the most common central nervous system (CNS) tumor in the pediatric population, yet displays subtle histologic differences. Previous studies have shown PMA to behave more aggressively than PA, with shorter progression-free and overall survival as well as a higher rate of recurrence and CNS dissemination. These findings suggest that PMA may be a unique and distinct neoplasm. This review summarizes the histologic, clinical, and radiographic characteristics of PMA. In addition, the current treatment options and research endeavors involving this disease are described. Increased recognition of PMA within the medical community has the potential to affect the treatment and prognosis of pediatric low-grade astrocytomas.

Original language	English (US)
Number of pages	1
Journal	MedGenMed : Medscape general medicine
Volume	6
Issue number	4
State	Published - 2004
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Cite this

@article{cbee5255e191423697d71e4d76f155d1,

title = "Pilomyxoid astrocytoma: a review.",

abstract = "Pilomyxoid astrocytoma (PMA) is a recently described type of brain tumor. PMA shares similar features with pilocytic astrocytoma (PA), the most common central nervous system (CNS) tumor in the pediatric population, yet displays subtle histologic differences. Previous studies have shown PMA to behave more aggressively than PA, with shorter progression-free and overall survival as well as a higher rate of recurrence and CNS dissemination. These findings suggest that PMA may be a unique and distinct neoplasm. This review summarizes the histologic, clinical, and radiographic characteristics of PMA. In addition, the current treatment options and research endeavors involving this disease are described. Increased recognition of PMA within the medical community has the potential to affect the treatment and prognosis of pediatric low-grade astrocytomas.",

author = "Komotar, {Ricardo J.} and J. Mocco and Carson, {Benjamin S.} and Sughrue, {Michael E.} and Zacharia, {Brad E.} and Sisti, {Alexander C.} and Canoll, {Peter D.} and Khandji, {Alexander G.} and Tarik Tihan and Burger, {Peter C.} and Bruce, {Jeffery N.}",

year = "2004",

language = "English (US)",

volume = "6",

journal = "MedGenMed : Medscape general medicine",

issn = "1531-0132",

publisher = "Medscape Health Network",

number = "4",

}

TY - JOUR

T1 - Pilomyxoid astrocytoma

T2 - a review.

AU - Komotar, Ricardo J.

AU - Mocco, J.

AU - Carson, Benjamin S.

AU - Sughrue, Michael E.

AU - Zacharia, Brad E.

AU - Sisti, Alexander C.

AU - Canoll, Peter D.

AU - Khandji, Alexander G.

AU - Tihan, Tarik

AU - Burger, Peter C.

AU - Bruce, Jeffery N.

PY - 2004

Y1 - 2004

N2 - Pilomyxoid astrocytoma (PMA) is a recently described type of brain tumor. PMA shares similar features with pilocytic astrocytoma (PA), the most common central nervous system (CNS) tumor in the pediatric population, yet displays subtle histologic differences. Previous studies have shown PMA to behave more aggressively than PA, with shorter progression-free and overall survival as well as a higher rate of recurrence and CNS dissemination. These findings suggest that PMA may be a unique and distinct neoplasm. This review summarizes the histologic, clinical, and radiographic characteristics of PMA. In addition, the current treatment options and research endeavors involving this disease are described. Increased recognition of PMA within the medical community has the potential to affect the treatment and prognosis of pediatric low-grade astrocytomas.

AB - Pilomyxoid astrocytoma (PMA) is a recently described type of brain tumor. PMA shares similar features with pilocytic astrocytoma (PA), the most common central nervous system (CNS) tumor in the pediatric population, yet displays subtle histologic differences. Previous studies have shown PMA to behave more aggressively than PA, with shorter progression-free and overall survival as well as a higher rate of recurrence and CNS dissemination. These findings suggest that PMA may be a unique and distinct neoplasm. This review summarizes the histologic, clinical, and radiographic characteristics of PMA. In addition, the current treatment options and research endeavors involving this disease are described. Increased recognition of PMA within the medical community has the potential to affect the treatment and prognosis of pediatric low-grade astrocytomas.

UR - http://www.scopus.com/inward/record.url?scp=33646822658&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33646822658&partnerID=8YFLogxK

M3 - Review article

C2 - 15775869

AN - SCOPUS:33646822658

SN - 1531-0132

VL - 6

JO - MedGenMed : Medscape general medicine

JF - MedGenMed : Medscape general medicine

IS - 4

ER -

Pilomyxoid astrocytoma: a review.

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this