Pierre Robin sequence: A perioperative review

Franklyn Cladis, Anand Kumar, Lorelei Grunwaldt, Todd Otteson, Matthew Ford, Joseph E. Losee

Research output: Contribution to journalArticle

Abstract

The clinical triad of micrognathia (small mandible), glossoptosis (backward, downward displacement of the tongue), and airway obstruction defines the Pierre Robin sequence (PRS). Airway obstruction and respiratory distress are clinical hallmarks. Patients may present with stridor, retractions, and cyanosis. Severe obstruction results in feeding difficulty, reflux, and failure to thrive. Treatment options depend on the severity of airway obstruction and include prone positioning, nasopharyngeal airways, tongue lip adhesion, mandibular distraction osteogenesis, and tracheostomy. The neonate and infant with PRS require care from multiple specialists including anesthesiology, plastic surgery, otolaryngology, speech pathology, gastroenterology, radiology, and neonatology. The anesthesiologist involved in the care of patients with PRS will interface with a multidisciplinary team in a variety of clinical settings. This perioperative review is a collaborative effort from multiple specialties including anesthesiology, plastic surgery, otolaryngology, and speech pathology. We will discuss the background and clinical presentation of patients with PRS, as well as some of the controversies regarding their care.

Original languageEnglish (US)
Pages (from-to)400-412
Number of pages13
JournalAnesthesia and Analgesia
Volume119
Issue number2
DOIs
StatePublished - 2014
Externally publishedYes

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Pierre Robin Syndrome
Airway Obstruction
Speech-Language Pathology
Anesthesiology
Otolaryngology
Plastic Surgery
Tongue
Micrognathism
Neonatology
Distraction Osteogenesis
Failure to Thrive
Cyanosis
Tracheostomy
Respiratory Sounds
Gastroenterology
Lip
Mandible
Radiology
Patient Care
Newborn Infant

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Cladis, F., Kumar, A., Grunwaldt, L., Otteson, T., Ford, M., & Losee, J. E. (2014). Pierre Robin sequence: A perioperative review. Anesthesia and Analgesia, 119(2), 400-412. https://doi.org/10.1213/ANE.0000000000000301

Pierre Robin sequence : A perioperative review. / Cladis, Franklyn; Kumar, Anand; Grunwaldt, Lorelei; Otteson, Todd; Ford, Matthew; Losee, Joseph E.

In: Anesthesia and Analgesia, Vol. 119, No. 2, 2014, p. 400-412.

Research output: Contribution to journalArticle

Cladis, F, Kumar, A, Grunwaldt, L, Otteson, T, Ford, M & Losee, JE 2014, 'Pierre Robin sequence: A perioperative review', Anesthesia and Analgesia, vol. 119, no. 2, pp. 400-412. https://doi.org/10.1213/ANE.0000000000000301
Cladis F, Kumar A, Grunwaldt L, Otteson T, Ford M, Losee JE. Pierre Robin sequence: A perioperative review. Anesthesia and Analgesia. 2014;119(2):400-412. https://doi.org/10.1213/ANE.0000000000000301
Cladis, Franklyn ; Kumar, Anand ; Grunwaldt, Lorelei ; Otteson, Todd ; Ford, Matthew ; Losee, Joseph E. / Pierre Robin sequence : A perioperative review. In: Anesthesia and Analgesia. 2014 ; Vol. 119, No. 2. pp. 400-412.
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