PI-RADS Steering Committee

The PI-RADS Multiparametric MRI and MRI-directed Biopsy Pathway

Anwar R. Padhani, Jelle Barentsz, Geert Villeirs, Andrew B. Rosenkrantz, Daniel J. Margolis, Baris Turkbey, Harriet C. Thoeny, François Cornud, Masoom A. Haider, Katarzyna Macura, Clare M. Tempany, Sadhna Verma, Jeffrey C. Weinreb

Research output: Contribution to journalArticle

Abstract

High-quality evidence shows that MRI in biopsy-naive men can reduce the number of men who need prostate biopsy and can reduce the number of diagnoses of clinically insignificant cancers that are unlikely to cause harm. In men with prior negative biopsy results who remain under persistent suspicion, MRI improves the detection and localization of life-threatening prostate cancer with greater clinical utility than the current standard of care, systematic transrectal US-guided biopsy. Systematic analyses show that MRI-directed biopsy increases the effectiveness of the prostate cancer diagnosis pathway. The incorporation of MRI-directed pathways into clinical care guidelines in prostate cancer detection has begun. The widespread adoption of the Prostate Imaging Reporting and Data System (PI-RADS) for multiparametric MRI data acquisition, interpretation, and reporting has promoted these changes in practice. The PI-RADS MRI-directed biopsy pathway enables the delivery of key diagnostic benefits to men suspected of having cancer based on clinical suspicion. Herein, the PI-RADS Steering Committee discusses how the MRI pathway should be incorporated into routine clinical practice and the challenges in delivering the positive health impacts needed by men suspected of having clinically significant prostate cancer.

Original languageEnglish (US)
Pages (from-to)464-474
Number of pages11
JournalRadiology
Volume292
Issue number2
DOIs
StatePublished - Jan 1 2019

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Information Systems
Prostate
Biopsy
Prostatic Neoplasms
Critical Pathways
Standard of Care
Neoplasms
Guidelines
Health

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Padhani, A. R., Barentsz, J., Villeirs, G., Rosenkrantz, A. B., Margolis, D. J., Turkbey, B., ... Weinreb, J. C. (2019). PI-RADS Steering Committee: The PI-RADS Multiparametric MRI and MRI-directed Biopsy Pathway. Radiology, 292(2), 464-474. https://doi.org/10.1148/radiol.2019182946

PI-RADS Steering Committee : The PI-RADS Multiparametric MRI and MRI-directed Biopsy Pathway. / Padhani, Anwar R.; Barentsz, Jelle; Villeirs, Geert; Rosenkrantz, Andrew B.; Margolis, Daniel J.; Turkbey, Baris; Thoeny, Harriet C.; Cornud, François; Haider, Masoom A.; Macura, Katarzyna; Tempany, Clare M.; Verma, Sadhna; Weinreb, Jeffrey C.

In: Radiology, Vol. 292, No. 2, 01.01.2019, p. 464-474.

Research output: Contribution to journalArticle

Padhani, AR, Barentsz, J, Villeirs, G, Rosenkrantz, AB, Margolis, DJ, Turkbey, B, Thoeny, HC, Cornud, F, Haider, MA, Macura, K, Tempany, CM, Verma, S & Weinreb, JC 2019, 'PI-RADS Steering Committee: The PI-RADS Multiparametric MRI and MRI-directed Biopsy Pathway', Radiology, vol. 292, no. 2, pp. 464-474. https://doi.org/10.1148/radiol.2019182946
Padhani AR, Barentsz J, Villeirs G, Rosenkrantz AB, Margolis DJ, Turkbey B et al. PI-RADS Steering Committee: The PI-RADS Multiparametric MRI and MRI-directed Biopsy Pathway. Radiology. 2019 Jan 1;292(2):464-474. https://doi.org/10.1148/radiol.2019182946
Padhani, Anwar R. ; Barentsz, Jelle ; Villeirs, Geert ; Rosenkrantz, Andrew B. ; Margolis, Daniel J. ; Turkbey, Baris ; Thoeny, Harriet C. ; Cornud, François ; Haider, Masoom A. ; Macura, Katarzyna ; Tempany, Clare M. ; Verma, Sadhna ; Weinreb, Jeffrey C. / PI-RADS Steering Committee : The PI-RADS Multiparametric MRI and MRI-directed Biopsy Pathway. In: Radiology. 2019 ; Vol. 292, No. 2. pp. 464-474.
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