Physiopathologie de la méningite tuberculeuse

Translated title of the contribution: Physiopathology of tuberculous meningitis

J. Grosset, H. Lecoeur, Ch Truffot-Pernot, V. Jarlier

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Due to the long division time of tubercle bacillus, the cell mediated immunity in tuberculosis and the prolonged persistence of the bacillus inside lesions, tuberculous meningitis has specific characteristics although it results, as other medical bacterial meningitis, from the extension of haematogenous lesions. Haematogenous dissemination occurs either during the formation of the primary complex and for some time afterwards when the infected host has not yet developed a specific immun response or years after the initial infection if the balance reached between dormant organisms and host is tipped in favour of the formers. Because tuberculous meningitis is slowly progressive but causes frequently irreversible damages, it should be diagnosed and treated as soon as possible. BCG vaccination which creates artificially a specific immune response reduces the incidence of tuberculous meningitis during childhood and should be continued wherever the risk of acquiring natural infection in high.

Translated title of the contributionPhysiopathology of tuberculous meningitis
Original languageFrench
Pages (from-to)593-596
Number of pages4
JournalMedecine et Maladies Infectieuses
Issue number10 PART 2
StatePublished - Oct 1985


  • BCG vaccination
  • Diagnosis
  • Meningitis
  • Mycobacterium tuberculosis
  • Physio-pathology

ASJC Scopus subject areas

  • Infectious Diseases


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