Physical activity and heart rate variability in older adults: The cardiovascular health study

Luisa Soares-Miranda, Jacob Sattelmair, Paulo Chaves, Glen E. Duncan, David S. Siscovick, Phyllis K. Stein, Dariush Mozaffarian

Research output: Contribution to journalArticle

Abstract

Background - Cardiac mortality and electrophysiological dysfunction both increase with age. Heart rate variability (HRV) provides indices of autonomic function and electrophysiology that are associated with cardiac risk. How habitual physical activity among older adults prospectively relates to HRV, including nonlinear indices of erratic sinus patterns, is not established. We hypothesized that increasing the levels of both total leisure-time activity and walking would be prospectively associated with more favorable time-domain, frequency-domain, and nonlinear HRV measures in older adults. Methods and Results - We evaluated serial longitudinal measures of both physical activity and 24-hour Holter HRV over 5 years among 985 older US adults in the community-based Cardiovascular Health Study. After multivariable adjustment, greater total leisure-time activity, walking distance, and walking pace were each prospectively associated with specific, more favorable HRV indices, including higher 24-hour standard deviation of all normal-to-normal intervals (Ptrend=0.009, 0.02, 0.06, respectively) and ultralow-frequency power (Ptrend=0.02, 0.008, 0.16, respectively). Greater walking pace was also associated with a higher short-term fractal scaling exponent (P trend=0.003) and lower Poincaré ratio (Ptrend=0.02) , markers of less erratic sinus patterns. Conclusions - Greater total leisure-time activity, and walking alone, as well, were prospectively associated with more favorable and specific indices of autonomic function in older adults, including several suggestive of more normal circadian fluctuations and less erratic sinoatrial firing. Our results suggest potential mechanisms that might contribute to lower cardiovascular mortality with habitual physical activity later in life.

Original languageEnglish (US)
Pages (from-to)2100-2110
Number of pages11
JournalCirculation
Volume129
Issue number21
DOIs
StatePublished - May 27 2014
Externally publishedYes

Fingerprint

Heart Rate
Leisure Activities
Health
Walking
Fractals
Mortality
Electrophysiology
Walking Speed

Keywords

  • Electrophysiology
  • Epidemiology
  • Exercise
  • Heart rate
  • Motor activity

ASJC Scopus subject areas

  • Physiology (medical)
  • Cardiology and Cardiovascular Medicine

Cite this

Soares-Miranda, L., Sattelmair, J., Chaves, P., Duncan, G. E., Siscovick, D. S., Stein, P. K., & Mozaffarian, D. (2014). Physical activity and heart rate variability in older adults: The cardiovascular health study. Circulation, 129(21), 2100-2110. https://doi.org/10.1161/CIRCULATIONAHA.113.005361

Physical activity and heart rate variability in older adults : The cardiovascular health study. / Soares-Miranda, Luisa; Sattelmair, Jacob; Chaves, Paulo; Duncan, Glen E.; Siscovick, David S.; Stein, Phyllis K.; Mozaffarian, Dariush.

In: Circulation, Vol. 129, No. 21, 27.05.2014, p. 2100-2110.

Research output: Contribution to journalArticle

Soares-Miranda, L, Sattelmair, J, Chaves, P, Duncan, GE, Siscovick, DS, Stein, PK & Mozaffarian, D 2014, 'Physical activity and heart rate variability in older adults: The cardiovascular health study', Circulation, vol. 129, no. 21, pp. 2100-2110. https://doi.org/10.1161/CIRCULATIONAHA.113.005361
Soares-Miranda L, Sattelmair J, Chaves P, Duncan GE, Siscovick DS, Stein PK et al. Physical activity and heart rate variability in older adults: The cardiovascular health study. Circulation. 2014 May 27;129(21):2100-2110. https://doi.org/10.1161/CIRCULATIONAHA.113.005361
Soares-Miranda, Luisa ; Sattelmair, Jacob ; Chaves, Paulo ; Duncan, Glen E. ; Siscovick, David S. ; Stein, Phyllis K. ; Mozaffarian, Dariush. / Physical activity and heart rate variability in older adults : The cardiovascular health study. In: Circulation. 2014 ; Vol. 129, No. 21. pp. 2100-2110.
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