Phototherapeutic keratectomy for climatic droplet keratopathy

Ihsan A. Badr, Ali Al-Rajhi, Michael D. Wagoner, Timithy Dunham, Klaus D. Teichmann, James A. Cameron, Wilfred Rademaker, Khalid Tabbara, Muneera Mahmood, Sobhi Antonios, Abdulrazzaq Al-Saif, Ali Al-Kaff, J. Miguel Risco

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Phototherapeutic keratectomy (PTK) is an effective treatment for many superficial corneal disorders. The efficacy of PTK for the treatment of climatic droplet keratopathy (CDK) has not been reported. METHODS: We report the results of excimer laser (Summit Technology, Inc, Waltham, Mass) PTK on 75 eyes (67 patients) with 'smooth' climatic droplet keratopathy (55 eyes) and 'irregular' climatic droplet keratopathy (20 eyes) in whom more than 6 months of follow up are available. RESULTS: PTK was successful in reducing corneal opacification in both smooth (98%) climatic droplet keratopathy and irregular (80%) climatic droplet keratopathy. Achievement of a clear or mildly hazy cornea following PTK was more likely to occur with smooth (80%) climatic droplet keratopathy than irregular (25%) climatic droplet keratopathy (P=0.01). Eyes with smooth climatic droplet keratopathy were more likely to obtain more than one line of improved uncorrected (56% vs. 25%) or spectacle-corrected visual acuity (61.8% vs. 21.2%) than those with irregular climatic droplet keratopathy (P=0.03 and 0.005, respectively). Delayed re-epithelialization (longer than 14 days) was more common in irregular CDK (21%) than in smooth CDK (9%), as was the incidence of secondary microbial keratitis (10.0% vs. 1.8%). CONCLUSIONS: PTK is effective in reducing superficial corneal opacification in CDK, although serious complications may occur, especially in advanced irregular CDK.

Original languageEnglish (US)
Pages (from-to)114-122
Number of pages9
JournalJournal of Refractive Surgery
Volume12
Issue number1
StatePublished - Jan 1996
Externally publishedYes

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Re-Epithelialization
Excimer Lasers
Keratitis
Cornea
Visual Acuity
Technology
Incidence
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Badr, I. A., Al-Rajhi, A., Wagoner, M. D., Dunham, T., Teichmann, K. D., Cameron, J. A., ... Risco, J. M. (1996). Phototherapeutic keratectomy for climatic droplet keratopathy. Journal of Refractive Surgery, 12(1), 114-122.

Phototherapeutic keratectomy for climatic droplet keratopathy. / Badr, Ihsan A.; Al-Rajhi, Ali; Wagoner, Michael D.; Dunham, Timithy; Teichmann, Klaus D.; Cameron, James A.; Rademaker, Wilfred; Tabbara, Khalid; Mahmood, Muneera; Antonios, Sobhi; Al-Saif, Abdulrazzaq; Al-Kaff, Ali; Risco, J. Miguel.

In: Journal of Refractive Surgery, Vol. 12, No. 1, 01.1996, p. 114-122.

Research output: Contribution to journalArticle

Badr, IA, Al-Rajhi, A, Wagoner, MD, Dunham, T, Teichmann, KD, Cameron, JA, Rademaker, W, Tabbara, K, Mahmood, M, Antonios, S, Al-Saif, A, Al-Kaff, A & Risco, JM 1996, 'Phototherapeutic keratectomy for climatic droplet keratopathy', Journal of Refractive Surgery, vol. 12, no. 1, pp. 114-122.
Badr IA, Al-Rajhi A, Wagoner MD, Dunham T, Teichmann KD, Cameron JA et al. Phototherapeutic keratectomy for climatic droplet keratopathy. Journal of Refractive Surgery. 1996 Jan;12(1):114-122.
Badr, Ihsan A. ; Al-Rajhi, Ali ; Wagoner, Michael D. ; Dunham, Timithy ; Teichmann, Klaus D. ; Cameron, James A. ; Rademaker, Wilfred ; Tabbara, Khalid ; Mahmood, Muneera ; Antonios, Sobhi ; Al-Saif, Abdulrazzaq ; Al-Kaff, Ali ; Risco, J. Miguel. / Phototherapeutic keratectomy for climatic droplet keratopathy. In: Journal of Refractive Surgery. 1996 ; Vol. 12, No. 1. pp. 114-122.
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abstract = "BACKGROUND: Phototherapeutic keratectomy (PTK) is an effective treatment for many superficial corneal disorders. The efficacy of PTK for the treatment of climatic droplet keratopathy (CDK) has not been reported. METHODS: We report the results of excimer laser (Summit Technology, Inc, Waltham, Mass) PTK on 75 eyes (67 patients) with 'smooth' climatic droplet keratopathy (55 eyes) and 'irregular' climatic droplet keratopathy (20 eyes) in whom more than 6 months of follow up are available. RESULTS: PTK was successful in reducing corneal opacification in both smooth (98{\%}) climatic droplet keratopathy and irregular (80{\%}) climatic droplet keratopathy. Achievement of a clear or mildly hazy cornea following PTK was more likely to occur with smooth (80{\%}) climatic droplet keratopathy than irregular (25{\%}) climatic droplet keratopathy (P=0.01). Eyes with smooth climatic droplet keratopathy were more likely to obtain more than one line of improved uncorrected (56{\%} vs. 25{\%}) or spectacle-corrected visual acuity (61.8{\%} vs. 21.2{\%}) than those with irregular climatic droplet keratopathy (P=0.03 and 0.005, respectively). Delayed re-epithelialization (longer than 14 days) was more common in irregular CDK (21{\%}) than in smooth CDK (9{\%}), as was the incidence of secondary microbial keratitis (10.0{\%} vs. 1.8{\%}). CONCLUSIONS: PTK is effective in reducing superficial corneal opacification in CDK, although serious complications may occur, especially in advanced irregular CDK.",
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AU - Al-Rajhi, Ali

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AU - Teichmann, Klaus D.

AU - Cameron, James A.

AU - Rademaker, Wilfred

AU - Tabbara, Khalid

AU - Mahmood, Muneera

AU - Antonios, Sobhi

AU - Al-Saif, Abdulrazzaq

AU - Al-Kaff, Ali

AU - Risco, J. Miguel

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N2 - BACKGROUND: Phototherapeutic keratectomy (PTK) is an effective treatment for many superficial corneal disorders. The efficacy of PTK for the treatment of climatic droplet keratopathy (CDK) has not been reported. METHODS: We report the results of excimer laser (Summit Technology, Inc, Waltham, Mass) PTK on 75 eyes (67 patients) with 'smooth' climatic droplet keratopathy (55 eyes) and 'irregular' climatic droplet keratopathy (20 eyes) in whom more than 6 months of follow up are available. RESULTS: PTK was successful in reducing corneal opacification in both smooth (98%) climatic droplet keratopathy and irregular (80%) climatic droplet keratopathy. Achievement of a clear or mildly hazy cornea following PTK was more likely to occur with smooth (80%) climatic droplet keratopathy than irregular (25%) climatic droplet keratopathy (P=0.01). Eyes with smooth climatic droplet keratopathy were more likely to obtain more than one line of improved uncorrected (56% vs. 25%) or spectacle-corrected visual acuity (61.8% vs. 21.2%) than those with irregular climatic droplet keratopathy (P=0.03 and 0.005, respectively). Delayed re-epithelialization (longer than 14 days) was more common in irregular CDK (21%) than in smooth CDK (9%), as was the incidence of secondary microbial keratitis (10.0% vs. 1.8%). CONCLUSIONS: PTK is effective in reducing superficial corneal opacification in CDK, although serious complications may occur, especially in advanced irregular CDK.

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