@inproceedings{f85f4d2c035d44fa8540ebb8d066bfde,
title = "Photoacoustic imaging of prostate brachytherapy seeds with transurethral light delivery",
abstract = "We present a novel approach to photoacoustic imaging of prostate brachytherapy seeds utilizing an existing urinary catheter for transurethral light delivery. Two canine prostates were surgically implanted with brachyther- apy seeds under transrectal ultrasound guidance. One prostate was excised shortly after euthanasia and fixed in gelatin. The second prostate was imaged in the native tissue environment shortly after euthanasia. A urinary catheter was inserted in the urethra of each prostate. A 1-mm core diameter optical fiber coupled to a 1064 nm Nd:YAG laser was inserted into the urinary catheter. Light from the fiber was either directed mostly parallel to the fiber axis (i.e. end-fire fire) or mostly 90°to the fiber axis (i.e. side-fire fiber). An Ultrasonix SonixTouch scanner, transrectal ultrasound probe with curvilinear (BPC8-4) and linear (BPL9-5) arrays, and DAQ unit were utilized for synchronized laser light emission and photoacoustic signal acquisition. The implanted brachytherapy seeds were visualized at radial distances of 6-16 mm from the catheter. Multiple brachytherapy seeds were si- multaneously visualized with each array of the transrectal probe using both delay-and-sum (DAS) and short-lag spatial coherence (SLSC) beamforming. This work is the first to demonstrate the feasibility of photoacoustic imaging of prostate brachytherapy seeds using a transurethral light delivery method.",
keywords = "Beamforming, Optoacoustic imaging, Prostate cancer, Side-fire probe, Side-looking probe",
author = "{Lediju Bell}, {Muyinatu A.} and Xiaoyu Guo and Song, {Danny Y.} and Boctor, {Emad M.}",
year = "2014",
month = jan,
day = "1",
doi = "10.1117/12.2040751",
language = "English (US)",
isbn = "9780819498564",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
booktitle = "Photons Plus Ultrasound",
note = "Photons Plus Ultrasound: Imaging and Sensing 2014 ; Conference date: 02-02-2014 Through 05-02-2014",
}