The phosphorylation of nuclear matrix proteins from normal and regenerating rat liver nuclei was examined using an in vitro system of isolated nuclei and γ-32P-ATP. Phosphorylation of the nuclear matrix proteins was 2-3 fold higher than that of the total nuclear proteins in normal nuclei. The level of phosphorylation of the matrix proteins was enhanced an additional three fold at a period in liver regeneration (12 hours) just preceding the onset of DNA synthesis.
|Original language||English (US)|
|Number of pages||6|
|Journal||Biochemical and Biophysical Research Communications|
|State||Published - Mar 7 1977|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology