Phosphorylation of nuclear matrix proteins in isolated regenerating rat liver nuclei

Steven L. Allen, Ronald Berezney, Donald S. Coffey

Research output: Contribution to journalArticlepeer-review

Abstract

The phosphorylation of nuclear matrix proteins from normal and regenerating rat liver nuclei was examined using an in vitro system of isolated nuclei and γ-32P-ATP. Phosphorylation of the nuclear matrix proteins was 2-3 fold higher than that of the total nuclear proteins in normal nuclei. The level of phosphorylation of the matrix proteins was enhanced an additional three fold at a period in liver regeneration (12 hours) just preceding the onset of DNA synthesis.

Original languageEnglish (US)
Pages (from-to)111-116
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume75
Issue number1
DOIs
StatePublished - Mar 7 1977

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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