Abstract
Phosgene (carbonyl chloride, CAS 75-44-5) is a highly reactive gas of historical interest and current industrial importance. Phosgene has also proved to be a useful model for the study of those biochemical mechanisms that lead to permeability-type pulmonary edema (adult respiratory distress syndrome). In turn, the study of phosgene-induced adult respiratory distress syndrome has provided insights leading to revised treatment strategies for exposure victims. We summarized recent findings on the mechanisms of phosgene-induced pulmonary edema and their implications for victim management. In light of that research, we also provide a comprehensive approach to the management and treatment of phosgene exposure victims.
Original language | English (US) |
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Pages (from-to) | 110-119 |
Number of pages | 10 |
Journal | Journal of occupational and environmental medicine |
Volume | 43 |
Issue number | 2 |
DOIs | |
State | Published - Jan 1 2001 |
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health