@article{902e6f2b5d8b41e181420a0f0b56b242,
title = "Phenotyping pulmonary hypertension in systemic sclerosis: a moving target",
author = "Valentina Mercurio and Hassoun, {Paul M.}",
note = "Funding Information: In conclusion, while observations from this study are useful for clinicians, they also highlight the concept that, when it comes to PH, phenotyping is crucial and should not solely rely on hemodynamic measurements and an arbitrary PAWP cutoff. Phenotyping and proper group assignment should emanate from a thorough evaluation of clinical characteristics, co-morbidities, imaging data (e.g. echocardiography, cardiac magnetic resonance, thoracic computed tomography), hemodynamic data including provocation maneuvers (e.g. exercise or fluid challenge), and probably much more. This is true whether for SSc but also other diseases associated with PH. This is indeed the very focus of an ongoing National Institutes of Health (NIH)/National Heart, Lung and Blood institute (NHLBI) sponsored initiative, the PVDOMICS (Redefining Pulmonary Hypertension through Pulmonary Vascular Disease Phenomics), which is aimed at augmenting the current PH classification based on shared biological features.10 The protocols and procedures are available online (https://pvdstudy.ccf.org/pvd/) and the results of these studies will be broadly available for future investigations.",
year = "2018",
month = apr,
day = "1",
doi = "10.1177/2045894018785247",
language = "English (US)",
volume = "8",
journal = "Pulmonary Circulation",
issn = "2045-8932",
publisher = "University of Chicago Press",
number = "2",
}