Phenotyping

Cory Brayton, Piper M. Treuting

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Coordinated systematic phenotyping of thousands of genetically engineered mice (GEM) with mutations in every protein coding gene, together with hypothesis-driven targeted phenotyping, has tremendous potential to inform and support diverse areas of translational biomedical research. Anatomy and histology phenotyping (pathology) is elemental to this ambitious endeavor. It is hoped that comparative atlases such as this will become essential tools for investigators conducting and reporting robust, reproducible, and relevant translational science, thus emulating Virchow and Osler in their recognition of the enduring relevance of comparative medicine and pathology. © 2012

Original languageEnglish (US)
Title of host publicationComparative Anatomy and Histology
PublisherElsevier Inc.
Pages7-14
Number of pages8
ISBN (Print)9780123813619
DOIs
StatePublished - Dec 1 2012

Keywords

  • Anatomy
  • Dysmorphology
  • Genetically engineered mice
  • Histology
  • International mouse phenotyping consortium
  • Mouse pathology
  • Pathobiology
  • Phenotyping

ASJC Scopus subject areas

  • Dentistry(all)
  • Medicine(all)

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  • Cite this

    Brayton, C., & Treuting, P. M. (2012). Phenotyping. In Comparative Anatomy and Histology (pp. 7-14). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-381361-9.00002-0