Phenotyping

Cory Brayton; Piper M. Treuting

doi:10.1016/B978-0-12-381361-9.00002-0

Phenotyping

Cory Brayton, Piper M. Treuting

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Coordinated systematic phenotyping of thousands of genetically engineered mice (GEM) with mutations in every protein coding gene, together with hypothesis-driven targeted phenotyping, has tremendous potential to inform and support diverse areas of translational biomedical research. Anatomy and histology phenotyping (pathology) is elemental to this ambitious endeavor. It is hoped that comparative atlases such as this will become essential tools for investigators conducting and reporting robust, reproducible, and relevant translational science, thus emulating Virchow and Osler in their recognition of the enduring relevance of comparative medicine and pathology. © 2012

Original language	English (US)
Title of host publication	Comparative Anatomy and Histology
Publisher	Elsevier Inc.
Pages	7-14
Number of pages	8
ISBN (Print)	9780123813619
DOIs	https://doi.org/10.1016/B978-0-12-381361-9.00002-0
State	Published - 2012

Keywords

Anatomy
Dysmorphology
Genetically engineered mice
Histology
International mouse phenotyping consortium
Mouse pathology
Pathobiology
Phenotyping

ASJC Scopus subject areas

General Dentistry
General Medicine

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10.1016/B978-0-12-381361-9.00002-0

Cite this

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AU - Treuting, Piper M.

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AB - Coordinated systematic phenotyping of thousands of genetically engineered mice (GEM) with mutations in every protein coding gene, together with hypothesis-driven targeted phenotyping, has tremendous potential to inform and support diverse areas of translational biomedical research. Anatomy and histology phenotyping (pathology) is elemental to this ambitious endeavor. It is hoped that comparative atlases such as this will become essential tools for investigators conducting and reporting robust, reproducible, and relevant translational science, thus emulating Virchow and Osler in their recognition of the enduring relevance of comparative medicine and pathology. © 2012

KW - Anatomy

KW - Dysmorphology

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KW - Histology

KW - International mouse phenotyping consortium

KW - Mouse pathology

KW - Pathobiology

KW - Phenotyping

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SN - 9780123813619

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BT - Comparative Anatomy and Histology

PB - Elsevier Inc.

ER -

Phenotyping

Abstract

Keywords

ASJC Scopus subject areas

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