Phase-sensitive Black-blood coronary vessel wall imaging

Khaled Z. Abd-Elmoniem, Robert George Weiss, Matthias Stuber

Research output: Contribution to journalArticle

Abstract

Black-blood MR coronary vessel wall imaging may become a powerful tool for the quantitative and noninvasive assessment of atherosclerosis and positive arterial remodeling. Although dual-inversion recovery is currently the gold standard, optimal lumen-to-vessel wall contrast is sometimes difficult to obtain, and the time window available for imaging is limited due to competing requirements between blood signal nulling time and period of minimal myocardial motion. Further, atherosclerosis is a spatially heterogeneous disease, and imaging at multiple anatomic levels of the coronary circulation is mandatory. However, this requirement of enhanced volumetric coverage comes at the expense of scanning time. Phase-sensitive inversion recovery has shown to be very valuable for enhancing tissue-tissue contrast and for making inversion recovery imaging less sensitive to tissue signal nulling time. This work enables multislice black-blood coronary vessel wall imaging in a single breath hold by extending phase-sensitive inversion recovery to phase-sensitive dual-inversion recovery, by combining it with spiral imaging and yet relaxing constraints related to blood signal nulling time and period of minimal myocardial motion.

Original languageEnglish (US)
Pages (from-to)1021-1030
Number of pages10
JournalMagnetic Resonance in Medicine
Volume63
Issue number4
DOIs
StatePublished - May 2010

Fingerprint

Blood Vessels
Coronary Vessels
Atherosclerosis
Coronary Circulation

Keywords

  • Black-blood
  • Coronary artery
  • Dual inversion
  • Inversion recovery
  • Phasesensitive
  • Vessel wall

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Phase-sensitive Black-blood coronary vessel wall imaging. / Abd-Elmoniem, Khaled Z.; Weiss, Robert George; Stuber, Matthias.

In: Magnetic Resonance in Medicine, Vol. 63, No. 4, 05.2010, p. 1021-1030.

Research output: Contribution to journalArticle

Abd-Elmoniem, Khaled Z. ; Weiss, Robert George ; Stuber, Matthias. / Phase-sensitive Black-blood coronary vessel wall imaging. In: Magnetic Resonance in Medicine. 2010 ; Vol. 63, No. 4. pp. 1021-1030.
@article{4f4818504273476cbc814b2abdee5ae6,
title = "Phase-sensitive Black-blood coronary vessel wall imaging",
abstract = "Black-blood MR coronary vessel wall imaging may become a powerful tool for the quantitative and noninvasive assessment of atherosclerosis and positive arterial remodeling. Although dual-inversion recovery is currently the gold standard, optimal lumen-to-vessel wall contrast is sometimes difficult to obtain, and the time window available for imaging is limited due to competing requirements between blood signal nulling time and period of minimal myocardial motion. Further, atherosclerosis is a spatially heterogeneous disease, and imaging at multiple anatomic levels of the coronary circulation is mandatory. However, this requirement of enhanced volumetric coverage comes at the expense of scanning time. Phase-sensitive inversion recovery has shown to be very valuable for enhancing tissue-tissue contrast and for making inversion recovery imaging less sensitive to tissue signal nulling time. This work enables multislice black-blood coronary vessel wall imaging in a single breath hold by extending phase-sensitive inversion recovery to phase-sensitive dual-inversion recovery, by combining it with spiral imaging and yet relaxing constraints related to blood signal nulling time and period of minimal myocardial motion.",
keywords = "Black-blood, Coronary artery, Dual inversion, Inversion recovery, Phasesensitive, Vessel wall",
author = "Abd-Elmoniem, {Khaled Z.} and Weiss, {Robert George} and Matthias Stuber",
year = "2010",
month = "5",
doi = "10.1002/mrm.22286",
language = "English (US)",
volume = "63",
pages = "1021--1030",
journal = "Magnetic Resonance in Medicine",
issn = "0740-3194",
publisher = "John Wiley and Sons Inc.",
number = "4",

}

TY - JOUR

T1 - Phase-sensitive Black-blood coronary vessel wall imaging

AU - Abd-Elmoniem, Khaled Z.

AU - Weiss, Robert George

AU - Stuber, Matthias

PY - 2010/5

Y1 - 2010/5

N2 - Black-blood MR coronary vessel wall imaging may become a powerful tool for the quantitative and noninvasive assessment of atherosclerosis and positive arterial remodeling. Although dual-inversion recovery is currently the gold standard, optimal lumen-to-vessel wall contrast is sometimes difficult to obtain, and the time window available for imaging is limited due to competing requirements between blood signal nulling time and period of minimal myocardial motion. Further, atherosclerosis is a spatially heterogeneous disease, and imaging at multiple anatomic levels of the coronary circulation is mandatory. However, this requirement of enhanced volumetric coverage comes at the expense of scanning time. Phase-sensitive inversion recovery has shown to be very valuable for enhancing tissue-tissue contrast and for making inversion recovery imaging less sensitive to tissue signal nulling time. This work enables multislice black-blood coronary vessel wall imaging in a single breath hold by extending phase-sensitive inversion recovery to phase-sensitive dual-inversion recovery, by combining it with spiral imaging and yet relaxing constraints related to blood signal nulling time and period of minimal myocardial motion.

AB - Black-blood MR coronary vessel wall imaging may become a powerful tool for the quantitative and noninvasive assessment of atherosclerosis and positive arterial remodeling. Although dual-inversion recovery is currently the gold standard, optimal lumen-to-vessel wall contrast is sometimes difficult to obtain, and the time window available for imaging is limited due to competing requirements between blood signal nulling time and period of minimal myocardial motion. Further, atherosclerosis is a spatially heterogeneous disease, and imaging at multiple anatomic levels of the coronary circulation is mandatory. However, this requirement of enhanced volumetric coverage comes at the expense of scanning time. Phase-sensitive inversion recovery has shown to be very valuable for enhancing tissue-tissue contrast and for making inversion recovery imaging less sensitive to tissue signal nulling time. This work enables multislice black-blood coronary vessel wall imaging in a single breath hold by extending phase-sensitive inversion recovery to phase-sensitive dual-inversion recovery, by combining it with spiral imaging and yet relaxing constraints related to blood signal nulling time and period of minimal myocardial motion.

KW - Black-blood

KW - Coronary artery

KW - Dual inversion

KW - Inversion recovery

KW - Phasesensitive

KW - Vessel wall

UR - http://www.scopus.com/inward/record.url?scp=77950618274&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950618274&partnerID=8YFLogxK

U2 - 10.1002/mrm.22286

DO - 10.1002/mrm.22286

M3 - Article

VL - 63

SP - 1021

EP - 1030

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

SN - 0740-3194

IS - 4

ER -