Pharmacologic approaches to therapy for casovagal syncope

Research output: Contribution to journalReview articlepeer-review


Vasovagal syncope is a common disorder of autonomic cardiovascular regulation. Many pharmacologic agents have been proposed as effective in the management of this condition based on nonrandomized clinical trials. Notably, only 3 agents - atenolol, midodrine, and paroxetine - have demonstrated efficacy in the treatment of vasovagal syncope in at least 1 prospective, randomized, placebo-controlled clinical trial. Other therapies commonly used in treating syncope include increased salt and fluid intake and fludrocortisone. In this review, we provide a summary of currently available data that support or question the use of various pharmacologic agents for treatment of vasovagal syncope.

Original languageEnglish (US)
Pages (from-to)20-25
Number of pages6
JournalAmerican Journal of Cardiology
Issue number8 SUPPL. 1
StatePublished - Oct 21 1999

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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