TY - JOUR
T1 - Pharmacologic approaches to therapy for casovagal syncope
AU - Calkins, Hugh
PY - 1999/10/21
Y1 - 1999/10/21
N2 - Vasovagal syncope is a common disorder of autonomic cardiovascular regulation. Many pharmacologic agents have been proposed as effective in the management of this condition based on nonrandomized clinical trials. Notably, only 3 agents - atenolol, midodrine, and paroxetine - have demonstrated efficacy in the treatment of vasovagal syncope in at least 1 prospective, randomized, placebo-controlled clinical trial. Other therapies commonly used in treating syncope include increased salt and fluid intake and fludrocortisone. In this review, we provide a summary of currently available data that support or question the use of various pharmacologic agents for treatment of vasovagal syncope.
AB - Vasovagal syncope is a common disorder of autonomic cardiovascular regulation. Many pharmacologic agents have been proposed as effective in the management of this condition based on nonrandomized clinical trials. Notably, only 3 agents - atenolol, midodrine, and paroxetine - have demonstrated efficacy in the treatment of vasovagal syncope in at least 1 prospective, randomized, placebo-controlled clinical trial. Other therapies commonly used in treating syncope include increased salt and fluid intake and fludrocortisone. In this review, we provide a summary of currently available data that support or question the use of various pharmacologic agents for treatment of vasovagal syncope.
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U2 - 10.1016/s0002-9149(99)00626-8
DO - 10.1016/s0002-9149(99)00626-8
M3 - Review article
C2 - 10568557
AN - SCOPUS:0032755397
SN - 0002-9149
VL - 84
SP - 20
EP - 25
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 8 SUPPL. 1
ER -