Pharmacokinetics of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors: The role of alpha-1-acid glycoprotein binding

Richard A. Graham, Bert L. Lum, Sravanthi Cheeti, Jin Yan Jin, Karin Jorga, Daniel D. Von Hoff, Charles M. Rudin, Josina C. Reddy, Jennifer A. Low, Patricia M. LoRusso

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Medicine & Life Sciences