Pharmaceuticals and personal care products in chicken meat and other food animal products: A market-basket pilot study

Patrick A. Baron, David C Love, Keeve Nachman

Research output: Contribution to journalArticle

Abstract

Pharmaceutical drugs are extensively used in industrial food animal production. We examined whether residues of veterinary antibiotics and other pharmaceuticals and personal care products (PPCPs) were detectable in a small market-basket sample of retail chicken (n = 39), ground beef (n = 3) and milk (n = 3) samples. High-performance liquid chromatography and tandem mass spectrometry were used to assess the concentration of 59 PPCPs and their residues in animal products. All samples of ground beef, milk, and 14 chickens were analyzed individually, while an additional 25 chicken samples were pooled and analyzed in groups of five. The majority of PPCPs were not detected in meat and milk samples. Caffeine was detected in two of three milk samples (0.4. ng/mL, 2.0. ng/mL) and in 10 of 19 individual and pooled chicken samples (median: 18.6. ng/g, range: 6.1-28.8. ng/g). Acetaminophen was detected in three of three milk samples (median: 1.5. ng/mL, range: 1.4-2.1. ng/mL). Antibiotics in the tetracycline class were detected in two of three milk samples (median: 1.0. ng/mL, range: 0.1-2.0. ng/mL) and did not exceed regulatory residue tolerances of 300. ng/mL. There are no regulatory residue tolerances for caffeine or acetaminophen in animal products. The acetaminophen detections in milk, however, raise questions about extra-label and unapproved use of pharmaceutical drugs in food animal production, as this drug is not approved for use in lactating dairy cattle or any other type of food animal production. Additional studies are needed to confirm our finding of PPCPs in meat and dairy products.

Original languageEnglish (US)
Pages (from-to)296-300
Number of pages5
JournalScience of the Total Environment
Volume490
DOIs
StatePublished - Aug 15 2014

Fingerprint

animal product
Pharmaceutical Services
Meats
meat
Drug products
Meat
milk
Chickens
Milk
Animals
Food
market
food
drug
Pharmaceutical Preparations
Acetaminophen
Caffeine
Beef
Antibiotics
antibiotics

Keywords

  • Antibiotics
  • Chicken
  • Ground beef
  • Milk
  • Pharmaceuticals
  • Residues

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution
  • Waste Management and Disposal
  • Environmental Engineering
  • Medicine(all)

Cite this

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title = "Pharmaceuticals and personal care products in chicken meat and other food animal products: A market-basket pilot study",
abstract = "Pharmaceutical drugs are extensively used in industrial food animal production. We examined whether residues of veterinary antibiotics and other pharmaceuticals and personal care products (PPCPs) were detectable in a small market-basket sample of retail chicken (n = 39), ground beef (n = 3) and milk (n = 3) samples. High-performance liquid chromatography and tandem mass spectrometry were used to assess the concentration of 59 PPCPs and their residues in animal products. All samples of ground beef, milk, and 14 chickens were analyzed individually, while an additional 25 chicken samples were pooled and analyzed in groups of five. The majority of PPCPs were not detected in meat and milk samples. Caffeine was detected in two of three milk samples (0.4. ng/mL, 2.0. ng/mL) and in 10 of 19 individual and pooled chicken samples (median: 18.6. ng/g, range: 6.1-28.8. ng/g). Acetaminophen was detected in three of three milk samples (median: 1.5. ng/mL, range: 1.4-2.1. ng/mL). Antibiotics in the tetracycline class were detected in two of three milk samples (median: 1.0. ng/mL, range: 0.1-2.0. ng/mL) and did not exceed regulatory residue tolerances of 300. ng/mL. There are no regulatory residue tolerances for caffeine or acetaminophen in animal products. The acetaminophen detections in milk, however, raise questions about extra-label and unapproved use of pharmaceutical drugs in food animal production, as this drug is not approved for use in lactating dairy cattle or any other type of food animal production. Additional studies are needed to confirm our finding of PPCPs in meat and dairy products.",
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