Abstract
Pharmaceutical drugs are extensively used in industrial food animal production. We examined whether residues of veterinary antibiotics and other pharmaceuticals and personal care products (PPCPs) were detectable in a small market-basket sample of retail chicken (n = 39), ground beef (n = 3) and milk (n = 3) samples. High-performance liquid chromatography and tandem mass spectrometry were used to assess the concentration of 59 PPCPs and their residues in animal products. All samples of ground beef, milk, and 14 chickens were analyzed individually, while an additional 25 chicken samples were pooled and analyzed in groups of five. The majority of PPCPs were not detected in meat and milk samples. Caffeine was detected in two of three milk samples (0.4. ng/mL, 2.0. ng/mL) and in 10 of 19 individual and pooled chicken samples (median: 18.6. ng/g, range: 6.1-28.8. ng/g). Acetaminophen was detected in three of three milk samples (median: 1.5. ng/mL, range: 1.4-2.1. ng/mL). Antibiotics in the tetracycline class were detected in two of three milk samples (median: 1.0. ng/mL, range: 0.1-2.0. ng/mL) and did not exceed regulatory residue tolerances of 300. ng/mL. There are no regulatory residue tolerances for caffeine or acetaminophen in animal products. The acetaminophen detections in milk, however, raise questions about extra-label and unapproved use of pharmaceutical drugs in food animal production, as this drug is not approved for use in lactating dairy cattle or any other type of food animal production. Additional studies are needed to confirm our finding of PPCPs in meat and dairy products.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 296-300 |
| Number of pages | 5 |
| Journal | Science of the Total Environment |
| Volume | 490 |
| DOIs | |
| State | Published - Aug 15 2014 |
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Keywords
- Antibiotics
- Chicken
- Ground beef
- Milk
- Pharmaceuticals
- Residues
ASJC Scopus subject areas
- Environmental Chemistry
- Pollution
- Waste Management and Disposal
- Environmental Engineering
- Medicine(all)
Cite this
Pharmaceuticals and personal care products in chicken meat and other food animal products : A market-basket pilot study. / Baron, Patrick A.; Love, David C; Nachman, Keeve.
In: Science of the Total Environment, Vol. 490, 15.08.2014, p. 296-300.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pharmaceuticals and personal care products in chicken meat and other food animal products
T2 - A market-basket pilot study
AU - Baron, Patrick A.
AU - Love, David C
AU - Nachman, Keeve
PY - 2014/8/15
Y1 - 2014/8/15
N2 - Pharmaceutical drugs are extensively used in industrial food animal production. We examined whether residues of veterinary antibiotics and other pharmaceuticals and personal care products (PPCPs) were detectable in a small market-basket sample of retail chicken (n = 39), ground beef (n = 3) and milk (n = 3) samples. High-performance liquid chromatography and tandem mass spectrometry were used to assess the concentration of 59 PPCPs and their residues in animal products. All samples of ground beef, milk, and 14 chickens were analyzed individually, while an additional 25 chicken samples were pooled and analyzed in groups of five. The majority of PPCPs were not detected in meat and milk samples. Caffeine was detected in two of three milk samples (0.4. ng/mL, 2.0. ng/mL) and in 10 of 19 individual and pooled chicken samples (median: 18.6. ng/g, range: 6.1-28.8. ng/g). Acetaminophen was detected in three of three milk samples (median: 1.5. ng/mL, range: 1.4-2.1. ng/mL). Antibiotics in the tetracycline class were detected in two of three milk samples (median: 1.0. ng/mL, range: 0.1-2.0. ng/mL) and did not exceed regulatory residue tolerances of 300. ng/mL. There are no regulatory residue tolerances for caffeine or acetaminophen in animal products. The acetaminophen detections in milk, however, raise questions about extra-label and unapproved use of pharmaceutical drugs in food animal production, as this drug is not approved for use in lactating dairy cattle or any other type of food animal production. Additional studies are needed to confirm our finding of PPCPs in meat and dairy products.
AB - Pharmaceutical drugs are extensively used in industrial food animal production. We examined whether residues of veterinary antibiotics and other pharmaceuticals and personal care products (PPCPs) were detectable in a small market-basket sample of retail chicken (n = 39), ground beef (n = 3) and milk (n = 3) samples. High-performance liquid chromatography and tandem mass spectrometry were used to assess the concentration of 59 PPCPs and their residues in animal products. All samples of ground beef, milk, and 14 chickens were analyzed individually, while an additional 25 chicken samples were pooled and analyzed in groups of five. The majority of PPCPs were not detected in meat and milk samples. Caffeine was detected in two of three milk samples (0.4. ng/mL, 2.0. ng/mL) and in 10 of 19 individual and pooled chicken samples (median: 18.6. ng/g, range: 6.1-28.8. ng/g). Acetaminophen was detected in three of three milk samples (median: 1.5. ng/mL, range: 1.4-2.1. ng/mL). Antibiotics in the tetracycline class were detected in two of three milk samples (median: 1.0. ng/mL, range: 0.1-2.0. ng/mL) and did not exceed regulatory residue tolerances of 300. ng/mL. There are no regulatory residue tolerances for caffeine or acetaminophen in animal products. The acetaminophen detections in milk, however, raise questions about extra-label and unapproved use of pharmaceutical drugs in food animal production, as this drug is not approved for use in lactating dairy cattle or any other type of food animal production. Additional studies are needed to confirm our finding of PPCPs in meat and dairy products.
KW - Antibiotics
KW - Chicken
KW - Ground beef
KW - Milk
KW - Pharmaceuticals
KW - Residues
UR - http://www.scopus.com/inward/record.url?scp=84901339663&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901339663&partnerID=8YFLogxK
U2 - 10.1016/j.scitotenv.2014.04.112
DO - 10.1016/j.scitotenv.2014.04.112
M3 - Article
C2 - 24858227
AN - SCOPUS:84901339663
VL - 490
SP - 296
EP - 300
JO - Science of the Total Environment
JF - Science of the Total Environment
SN - 0048-9697
ER -