Abstract
Personalized medicine can be defined broadly as a model of healthcare that is predictive, personalized, preventive and participatory. Two US Presidents Council of Advisors on Science and Technology reports illustrate challenges in personalized medicine (in a 2008 report) and in use of health information technology (in a 2010 report). Translational bioinformatics is a field that can help address these challenges and is defined by the American Medical Informatics Association as "the development of storage, analytic and interpretive methods to optimize the transformation of increasing voluminous biomedical data into proactive, predictive, preventative and participatory health." This article discusses barriers to implementing genomics applications and current progress toward overcoming barriers, describes lessons learned from early experiences of institutions engaged in personalized medicine and provides example areas for translational bioinformatics research inquiry.
Original language | English (US) |
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Pages (from-to) | 453-462 |
Number of pages | 10 |
Journal | Personalized Medicine |
Volume | 10 |
Issue number | 5 |
DOIs | |
State | Published - Jul 2013 |
Externally published | Yes |
Keywords
- biobanks
- clinical decision support
- computational analyse
- education
- electronic health records
- implementation challenges
- individual research results
- personalized medicine
- translational bioinformatics
- translational research
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology