Abstract
Objective: To determine the personal characteristics and reasons associated with providing a buccal swab for apolipoprotein E (APOE) genetic testing in a primary care study. Methods: The study sample consisted of 342 adults aged 65 years and older recruited from primary care settings. Results: In all, 88% of patients agreed to provide a DNA sample for APOE genotyping and 78% of persons providing a sample agreed to banking of the DNA. Persons aged 80 years and older and African-Americans were less likely to participate in APOE genotyping. Concern about confidentiality was the most common reason for not wanting to provide a DNA sample or to have DNA banked. Conclusion: We found stronger relationships between sociodemographic variables of age and ethnicity with participation in genetic testing than we did between level of educational attainment, gender, function, cognition, and affect.
Original language | English (US) |
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Pages (from-to) | 202-210 |
Number of pages | 9 |
Journal | Community genetics |
Volume | 7 |
Issue number | 4 |
DOIs | |
State | Published - 2005 |
Keywords
- Apolipoprotein E
- Genetic testing
- Older adults
- Participant recruitment
- Race
ASJC Scopus subject areas
- Genetics(clinical)