Abstract
Background: Immigrants to developed countries have low rates of aeroallergen sensitization and asthma, but less is known about both food allergy and the role of parental immigration status. Objective: We sought to evaluate the relationship between personal and parental nativity and the risk of food sensitization. Methods: Three thousand five hundred fifty subjects less than 21 years old from the Nation Health and Examination Survey 2005-2006 were included. Odds ratios (ORs) were generated by using logistic regression, which adjusted for race/ethnicity, sex, age, and household income and accounted for the complex survey design. Nativity was classified as US-born or foreign-born, and the age of immigration was estimated. Head-of-household nativity was used as a proxy for parental nativity. Food sensitization was defined as at least 1 specific IgE level of 0.35 kU/L or greater to milk, egg, or peanut. Aeroallergen-specific sensitizations and the presence of asthma, allergic rhinitis, or eczema were also assessed. Results: Compared with those born outside the United States (US), US-born children and adolescents had higher odds of sensitization to any food (OR, 2.05; 95% CI, 1.49-2.83; P
| Original language | English (US) |
|---|---|
| Journal | The Journal of Allergy and Clinical Immunology |
| Volume | 129 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2012 |
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Keywords
- aeroallergen
- asthma
- child
- eczema
- Food allergy
- food sensitization
- hay fever
- immigration
- nativity
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
Cite this
Personal and parental nativity as risk factors for food sensitization. / Keet, Corinne; Wood, Robert A; Matsui, Elizabeth C.
In: The Journal of Allergy and Clinical Immunology, Vol. 129, No. 1, 01.2012.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Personal and parental nativity as risk factors for food sensitization
AU - Keet, Corinne
AU - Wood, Robert A
AU - Matsui, Elizabeth C.
PY - 2012/1
Y1 - 2012/1
N2 - Background: Immigrants to developed countries have low rates of aeroallergen sensitization and asthma, but less is known about both food allergy and the role of parental immigration status. Objective: We sought to evaluate the relationship between personal and parental nativity and the risk of food sensitization. Methods: Three thousand five hundred fifty subjects less than 21 years old from the Nation Health and Examination Survey 2005-2006 were included. Odds ratios (ORs) were generated by using logistic regression, which adjusted for race/ethnicity, sex, age, and household income and accounted for the complex survey design. Nativity was classified as US-born or foreign-born, and the age of immigration was estimated. Head-of-household nativity was used as a proxy for parental nativity. Food sensitization was defined as at least 1 specific IgE level of 0.35 kU/L or greater to milk, egg, or peanut. Aeroallergen-specific sensitizations and the presence of asthma, allergic rhinitis, or eczema were also assessed. Results: Compared with those born outside the United States (US), US-born children and adolescents had higher odds of sensitization to any food (OR, 2.05; 95% CI, 1.49-2.83; P
AB - Background: Immigrants to developed countries have low rates of aeroallergen sensitization and asthma, but less is known about both food allergy and the role of parental immigration status. Objective: We sought to evaluate the relationship between personal and parental nativity and the risk of food sensitization. Methods: Three thousand five hundred fifty subjects less than 21 years old from the Nation Health and Examination Survey 2005-2006 were included. Odds ratios (ORs) were generated by using logistic regression, which adjusted for race/ethnicity, sex, age, and household income and accounted for the complex survey design. Nativity was classified as US-born or foreign-born, and the age of immigration was estimated. Head-of-household nativity was used as a proxy for parental nativity. Food sensitization was defined as at least 1 specific IgE level of 0.35 kU/L or greater to milk, egg, or peanut. Aeroallergen-specific sensitizations and the presence of asthma, allergic rhinitis, or eczema were also assessed. Results: Compared with those born outside the United States (US), US-born children and adolescents had higher odds of sensitization to any food (OR, 2.05; 95% CI, 1.49-2.83; P
KW - aeroallergen
KW - asthma
KW - child
KW - eczema
KW - Food allergy
KW - food sensitization
KW - hay fever
KW - immigration
KW - nativity
UR - http://www.scopus.com/inward/record.url?scp=84455169535&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84455169535&partnerID=8YFLogxK
U2 - 10.1016/j.jaci.2011.10.002
DO - 10.1016/j.jaci.2011.10.002
M3 - Article
C2 - 22075329
AN - SCOPUS:84455169535
VL - 129
JO - Journal of Allergy and Clinical Immunology
JF - Journal of Allergy and Clinical Immunology
SN - 0091-6749
IS - 1
ER -