Abstract
Background: A significant proportion of norovirus (NV) gastroenteritis outbreaks described in the Spanish literature have been because of contaminated food or water. Aim: This study describes an outbreak of acute gastroenteritis because of NV in which there was person-toperson transmission. Materials and methods: A retrospective cohort study was carried out; we established the case definition for primary and secondary cases. An epidemiological survey was designed, including possible food exposures, and clinical and laboratory data. Water and stool samples were taken from affected individuals and food handlers. The presence of NV was detected using a reverse transcription-PCR assay. We analyzed the risk of gastroenteritis using relative risk and its 95% confidence interval as the measure of association, and estimated the basic reproductive number (R0). Results: The primary attack rate was 45.0%, with no significant differences between sexes. The secondary attack rate during the camp stay was 22.7%. The basic reproductive number for 5 days was R0=2.62. The most frequent symptoms were abdominal pain (85.7%) and vomiting (81.9%). Epidemiological analysis showed no association with food or drinking water. A total of 66.6% (8/12) of stool samples tested positive for NV (genogroup II). Conclusion: Control measures in general, and hand hygiene in particular, should be extended to the families once the children return home, to prevent secondary cases in NV outbreaks.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1160-1166 |
| Number of pages | 7 |
| Journal | European Journal of Gastroenterology and Hepatology |
| Volume | 26 |
| Issue number | 10 |
| DOIs | |
| State | Published - 2014 |
| Externally published | Yes |
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Keywords
- Acute gastroenteritis
- Epidemiology
- Norovirus
- Outbreaks
- Person-to-person transmission
ASJC Scopus subject areas
- Gastroenterology
- Hepatology
- Medicine(all)
Cite this
Person-to-person transmission of norovirus resulting in an outbreak of acute gastroenteritis at a summer camp. / Solano, Rubén; Alseda, Miquel; Godoy, Pere; Sanz, Milagros; Bartolomé, Rosa; Manzanares-Laya, Sandra; Domínguez, Ángela; Caylà, Joan A.
In: European Journal of Gastroenterology and Hepatology, Vol. 26, No. 10, 2014, p. 1160-1166.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Person-to-person transmission of norovirus resulting in an outbreak of acute gastroenteritis at a summer camp
AU - Solano, Rubén
AU - Alseda, Miquel
AU - Godoy, Pere
AU - Sanz, Milagros
AU - Bartolomé, Rosa
AU - Manzanares-Laya, Sandra
AU - Domínguez, Ángela
AU - Caylà, Joan A.
PY - 2014
Y1 - 2014
N2 - Background: A significant proportion of norovirus (NV) gastroenteritis outbreaks described in the Spanish literature have been because of contaminated food or water. Aim: This study describes an outbreak of acute gastroenteritis because of NV in which there was person-toperson transmission. Materials and methods: A retrospective cohort study was carried out; we established the case definition for primary and secondary cases. An epidemiological survey was designed, including possible food exposures, and clinical and laboratory data. Water and stool samples were taken from affected individuals and food handlers. The presence of NV was detected using a reverse transcription-PCR assay. We analyzed the risk of gastroenteritis using relative risk and its 95% confidence interval as the measure of association, and estimated the basic reproductive number (R0). Results: The primary attack rate was 45.0%, with no significant differences between sexes. The secondary attack rate during the camp stay was 22.7%. The basic reproductive number for 5 days was R0=2.62. The most frequent symptoms were abdominal pain (85.7%) and vomiting (81.9%). Epidemiological analysis showed no association with food or drinking water. A total of 66.6% (8/12) of stool samples tested positive for NV (genogroup II). Conclusion: Control measures in general, and hand hygiene in particular, should be extended to the families once the children return home, to prevent secondary cases in NV outbreaks.
AB - Background: A significant proportion of norovirus (NV) gastroenteritis outbreaks described in the Spanish literature have been because of contaminated food or water. Aim: This study describes an outbreak of acute gastroenteritis because of NV in which there was person-toperson transmission. Materials and methods: A retrospective cohort study was carried out; we established the case definition for primary and secondary cases. An epidemiological survey was designed, including possible food exposures, and clinical and laboratory data. Water and stool samples were taken from affected individuals and food handlers. The presence of NV was detected using a reverse transcription-PCR assay. We analyzed the risk of gastroenteritis using relative risk and its 95% confidence interval as the measure of association, and estimated the basic reproductive number (R0). Results: The primary attack rate was 45.0%, with no significant differences between sexes. The secondary attack rate during the camp stay was 22.7%. The basic reproductive number for 5 days was R0=2.62. The most frequent symptoms were abdominal pain (85.7%) and vomiting (81.9%). Epidemiological analysis showed no association with food or drinking water. A total of 66.6% (8/12) of stool samples tested positive for NV (genogroup II). Conclusion: Control measures in general, and hand hygiene in particular, should be extended to the families once the children return home, to prevent secondary cases in NV outbreaks.
KW - Acute gastroenteritis
KW - Epidemiology
KW - Norovirus
KW - Outbreaks
KW - Person-to-person transmission
UR - http://www.scopus.com/inward/record.url?scp=84927691088&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84927691088&partnerID=8YFLogxK
U2 - 10.1097/MEG.0000000000000179
DO - 10.1097/MEG.0000000000000179
M3 - Article
C2 - 25117826
AN - SCOPUS:84927691088
VL - 26
SP - 1160
EP - 1166
JO - European Journal of Gastroenterology and Hepatology
JF - European Journal of Gastroenterology and Hepatology
SN - 0954-691X
IS - 10
ER -