Persistent SIRS and acute fluid collections are associated with increased CT scanning in acute interstitial pancreatitis

Ayesha Kamal, Mahya Faghih, Robert A. Moran, Elham Afghani, Amitasha Sinha, Nasim Parsa, Martin A Makary, Atif Zaheer, Elliot K Fishman, Mouen Khashab, Anthony N Kalloo, Vikesh Singh

Research output: Contribution to journalArticlepeer-review


Background: The use of computed tomography (CT) in acute pancreatitis (AP) continues to increase in parallel with the increasing use of diagnostic imaging in clinical medicine. Aim: To determine the factors associated with obtaining >1 CT scan in acute interstitial pancreatitis (AIP). Methods: Demographic and clinical data of all adult patients admitted between 1/2010 and 1/2015 with AP (AP) were evaluated. Only patients with a CT severity index (CTSI) ≤ 3 on a CT obtained within 48 h of presentation were included. Results: A total of 229 patients were included, of whom 206 (90%) had a single CT and 23 (10%) had >1 CT during the first week of hospitalization. Patients undergoing >1 CT had significantly higher rates of acute fluid collection (AFC), persistent SIRS, opioid use ≥4 days, and persistent organ failure compared to those undergoing 1 CT (p < .05 for all). On multivariable analysis, only persistent SIRS (OR = 3.6, 95% CI 1.4–9.6, p = .01) and an AFC on initial CT (OR = 3.5, 95% CI 1.4–9, p = .009) were independently associated with obtaining >1 CT. Conclusion: An AFC on initial CT and persistent SIRS are associated with increased CT imaging in AIP patients. However, these additional CT scans did not change clinical management.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalScandinavian Journal of Gastroenterology
StateAccepted/In press - Oct 5 2017


  • acute fluid collection
  • Acute pancreatitis
  • CT scans
  • persistent SIRS

ASJC Scopus subject areas

  • Gastroenterology


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