Persistence of alphaviruses in vertebrate hosts

Beth Levine; J. Marie Hardwick; Diane E. Griffin

doi:10.1016/0966-842X(94)90341-7

Persistence of alphaviruses in vertebrate hosts

Beth Levine, J. Marie Hardwick, Diane E. Griffin

Bloomberg School of Public Health

Research output: Contribution to journal › Review article › peer-review

40 Scopus citations

Abstract

Alphaviruses are a group of arthropod-borne, positive-strand RNA viruses that cause acute encephalitis or arthritis. These viruses were previously thought to cause only acute infections in vertebrates, but recent evidence suggests that host immunological and tissue-specific factors may act together to promote the persistence of alphavirus genomes in vivo.

Original language	English (US)
Pages (from-to)	25-28
Number of pages	4
Journal	Trends in Microbiology
Volume	2
Issue number	1
DOIs	https://doi.org/10.1016/0966-842X(94)90341-7
State	Published - Jan 1994

ASJC Scopus subject areas

Microbiology
Microbiology (medical)
Virology
Infectious Diseases

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10.1016/0966-842X(94)90341-7

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title = "Persistence of alphaviruses in vertebrate hosts",

abstract = "Alphaviruses are a group of arthropod-borne, positive-strand RNA viruses that cause acute encephalitis or arthritis. These viruses were previously thought to cause only acute infections in vertebrates, but recent evidence suggests that host immunological and tissue-specific factors may act together to promote the persistence of alphavirus genomes in vivo.",

author = "Beth Levine and {Marie Hardwick}, J. and Griffin, {Diane E.}",

note = "Funding Information: Work from our laboratory was supported by US Public Health Service research grants NS29234, NS07000 and NS18596.",

year = "1994",

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AU - Griffin, Diane E.

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N2 - Alphaviruses are a group of arthropod-borne, positive-strand RNA viruses that cause acute encephalitis or arthritis. These viruses were previously thought to cause only acute infections in vertebrates, but recent evidence suggests that host immunological and tissue-specific factors may act together to promote the persistence of alphavirus genomes in vivo.

AB - Alphaviruses are a group of arthropod-borne, positive-strand RNA viruses that cause acute encephalitis or arthritis. These viruses were previously thought to cause only acute infections in vertebrates, but recent evidence suggests that host immunological and tissue-specific factors may act together to promote the persistence of alphavirus genomes in vivo.

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Persistence of alphaviruses in vertebrate hosts

Abstract

ASJC Scopus subject areas

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