PERIVASCULAR GRANULOMATA IN THE RETINA DEMONSTRATED BY EN FACE OPTICAL COHERENCE TOMOGRAPHY IN A PATIENT WITH BLAU SYNDROME

Erika T. Friesen, Nopasak Phasukkijwatana, Irena Tsui, Meghan Berkenstock, Gary N. Holland, David Sarraf

Research output: Contribution to journalArticle

Abstract

PURPOSE: To describe the multimodal retinal imaging findings of a case of Blau syndrome.

METHODS: Case report. The multimodal retinal imaging findings, including widefield angiography, cross-sectional and en face spectral domain optical coherence tomography, and optical coherence tomography angiography, of a case of Blau syndrome are described.

RESULTS: A 12-year-old Hispanic girl with polyarticular arthritis, skin rash, and panuveitis was diagnosed with a rare condition referred to as Blau syndrome. Genetic testing identified an NOD2 mutation. Cross-sectional and en face optical coherence tomography illustrated presumed perivascular granulomata in the middle retina. Optical coherence tomography angiography failed to display flow within these lesions.

CONCLUSION: This report illustrates the presence of a remarkable distribution of perivascular, presumably granulomatous, retinal lesions in the middle retina. Similar perivascular granulomata have been noted in the histopathological analysis of ocular sarcoidosis.

Original languageEnglish (US)
Pages (from-to)S29-S32
JournalRetinal cases & brief reports
Volume12
DOIs
StatePublished - Sep 1 2018

ASJC Scopus subject areas

  • Ophthalmology

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