TY - JOUR
T1 - Peripheral nerve sheath tumors of the breast
AU - Charu, Vivek
AU - Cimino-Mathews, Ashley
N1 - Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2017/9
Y1 - 2017/9
N2 - Benign and malignant peripheral nerve sheath tumors can involve the breast, presenting as masses in the dermis, deep breast parenchyma or axillary soft tissue. Although the histologic features are frequently characteristic, diagnosis can be challenging on core needle biopsy, and the differential diagnosis includes a variety of other benign and malignant spindle cell lesions of the breast. Here, we review the key clinical and pathological features of breast schwannoma, neurofibroma, granular cell tumor, and malignant peripheral nerve sheath tumor.
AB - Benign and malignant peripheral nerve sheath tumors can involve the breast, presenting as masses in the dermis, deep breast parenchyma or axillary soft tissue. Although the histologic features are frequently characteristic, diagnosis can be challenging on core needle biopsy, and the differential diagnosis includes a variety of other benign and malignant spindle cell lesions of the breast. Here, we review the key clinical and pathological features of breast schwannoma, neurofibroma, granular cell tumor, and malignant peripheral nerve sheath tumor.
KW - Breast
KW - Granular cell tumor
KW - MNPST
KW - Neurofibroma
KW - Peripheral nerve sheath tumor
KW - Schwannoma
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U2 - 10.1053/j.semdp.2017.05.011
DO - 10.1053/j.semdp.2017.05.011
M3 - Review article
C2 - 28647116
AN - SCOPUS:85021178851
SN - 0740-2570
VL - 34
SP - 420
EP - 426
JO - Seminars in Diagnostic Pathology
JF - Seminars in Diagnostic Pathology
IS - 5
ER -