TY - JOUR
T1 - Peripheral arterial disease and chronic heart failure
T2 - A dangerous mix
AU - Inglis, Sally C.
AU - Hermis, Adriana
AU - Shehab, Sajad
AU - Newton, Phillip J.
AU - Lal, Sara
AU - Davidson, Patricia M.
N1 - Funding Information:
Acknowledgments Dr Sally C Inglis is a post-doctoral research fellow supported by the National Health and Medical Research Council of Australia (NHMRC) and National Heart Foundation of Australia (NHMRC Grant ID 472 699). Dr Inglis is a member of the National Health and Medical Research Council funded National Centre of Research Excellence for Peripheral Arterial Disease (NCRE-PAD). Dr Phillip J Newton is a post-doctoral research fellow supported by a Chancellor’s Post-Doctoral Fellowship from the University of Technology Sydney. Dr Sally C Inglis, Ms Adriana Hermis, Mr Sajad Shehab, Dr Phillip J Newton, Associate Professor Sara Lal and Professor Patricia M Davidson have no financial relationship with any pharmaceutical or device company.
PY - 2013/7
Y1 - 2013/7
N2 - Chronic heart failure (CHF) is associated with a high comorbidity burden, adverse impact on quality of life and high health care utilisation. Peripheral arterial disease (PAD) and CHF share many risk, pathophysiological and prognostic features, and each has been associated with increased morbidity and mortality. PAD often goes undetected, and yet in spite of the availability of screening tools, this is not commonly considered in CHF care. A review of the electronic databases Medline, CINAHL and Cochrane CENTRAL was undertaken using the MeSH terms peripheral arterial disease, peripheral vascular disease, intermittent claudication and heart failure to identify studies examining the prevalence and clinical outcomes of coexisting PAD in patients with CHF. Five studies were identified. There are limited data describing the impact of PAD on CHF outcomes. As PAD may contribute to decreased capacity to exercise and other self-care behaviours, identifying those at risk and providing appropriate therapy are important. Based on this review, patients who are smokers and those with diagnosed coronary heart disease and diabetes should be targeted for the screening of PAD.
AB - Chronic heart failure (CHF) is associated with a high comorbidity burden, adverse impact on quality of life and high health care utilisation. Peripheral arterial disease (PAD) and CHF share many risk, pathophysiological and prognostic features, and each has been associated with increased morbidity and mortality. PAD often goes undetected, and yet in spite of the availability of screening tools, this is not commonly considered in CHF care. A review of the electronic databases Medline, CINAHL and Cochrane CENTRAL was undertaken using the MeSH terms peripheral arterial disease, peripheral vascular disease, intermittent claudication and heart failure to identify studies examining the prevalence and clinical outcomes of coexisting PAD in patients with CHF. Five studies were identified. There are limited data describing the impact of PAD on CHF outcomes. As PAD may contribute to decreased capacity to exercise and other self-care behaviours, identifying those at risk and providing appropriate therapy are important. Based on this review, patients who are smokers and those with diagnosed coronary heart disease and diabetes should be targeted for the screening of PAD.
KW - Chronic heart failure
KW - Function
KW - Mortality
KW - Outcomes
KW - Peripheral arterial disease
KW - Prevalence
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U2 - 10.1007/s10741-012-9331-1
DO - 10.1007/s10741-012-9331-1
M3 - Review article
C2 - 22723049
AN - SCOPUS:84879069911
SN - 1382-4147
VL - 18
SP - 457
EP - 464
JO - Heart Failure Reviews
JF - Heart Failure Reviews
IS - 4
ER -