Perioperative participation of orthopedic patients and surgical staff in a nasal decolonization intervention to reduce Staphylococcus spp surgical site infections

Anildaliz Mullen, Helen J. Wieland, Eric S. Wieser, Ernst W Spannhake, Rebecca S. Marinos

Research output: Contribution to journalArticle


With the goal of reducing rates of surgical site infections in our spine patients, we initiated a trial to investigate the impact of adding perisurgical nasal decolonization involving patients and surgical and nursing staff. We combined immediate presurgical application of a nonantibiotic alcohol-based nasal antiseptic with existing chlorhexidine bath or wipes in a comprehensive pre- and postoperative decolonization protocol. Mean infection rates were significantly decreased by 81% from 1.76 to 0.33 per 100 surgeries during the 15-month trial, when compared with the prior 9-month baseline.

Original languageEnglish (US)
Pages (from-to)554-556
Number of pages3
JournalAmerican Journal of Infection Control
Issue number5
Publication statusPublished - May 1 2017



  • Alcohol-based nasal antiseptic
  • Anterior nares
  • Perioperative nasal decolonization
  • Spine surgery
  • Staff nasal decolonization

ASJC Scopus subject areas

  • Epidemiology
  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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