Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events: A randomized clinical trial

Steven Mark Frank, Lee A. Fleisher, Michael J. Breslow, Michael S. Higgins, Krista F. Olson, Susan Kelly, Charles Beattie

Research output: Contribution to journalArticle

Abstract

Objective.-To assess the relationship between body temperature and cardiac morbidity during the perioperative period. Design.-Randomized controlled trial comparing routine thermal care (hypothermic group) to additional supplemental warming care (normothermic group). Setting.-Operating rooms and surgical intensive care unit at an academic medical center. Subjects.-Three hundred patients undergoing abdominal, thoracic, or vascular surgical procedures who either had documented coronary artery disease or were at high risk for coronary disease. Outcome Measure.-The relative risk of a morbid cardiac event (unstable angina/ischemia, cardiac arrest, or myocardial infarction) according to thermal treatment. Cardiac outcomes were assessed in a double-blind fashion. Results.-Mean core temperature after surgery was lower in the hypothermic group (35.4±0.1°c) than in the normothermic group (36.7±0.1 °C) (P

Original languageEnglish (US)
Pages (from-to)1127-1134
Number of pages8
JournalJournal of the American Medical Association
Volume277
Issue number14
StatePublished - Apr 9 1997

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Thoracic Surgical Procedures
Vascular Surgical Procedures
Randomized Controlled Trials
Hot Temperature
Maintenance
Perioperative Period
Incidence
Unstable Angina
Operating Rooms
Critical Care
Heart Arrest
Body Temperature
Coronary Disease
Intensive Care Units
Coronary Artery Disease
Ischemia
Myocardial Infarction
Outcome Assessment (Health Care)
Morbidity
Temperature

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Frank, S. M., Fleisher, L. A., Breslow, M. J., Higgins, M. S., Olson, K. F., Kelly, S., & Beattie, C. (1997). Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events: A randomized clinical trial. Journal of the American Medical Association, 277(14), 1127-1134.

Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events : A randomized clinical trial. / Frank, Steven Mark; Fleisher, Lee A.; Breslow, Michael J.; Higgins, Michael S.; Olson, Krista F.; Kelly, Susan; Beattie, Charles.

In: Journal of the American Medical Association, Vol. 277, No. 14, 09.04.1997, p. 1127-1134.

Research output: Contribution to journalArticle

Frank, SM, Fleisher, LA, Breslow, MJ, Higgins, MS, Olson, KF, Kelly, S & Beattie, C 1997, 'Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events: A randomized clinical trial' Journal of the American Medical Association, vol. 277, no. 14, pp. 1127-1134.
Frank, Steven Mark ; Fleisher, Lee A. ; Breslow, Michael J. ; Higgins, Michael S. ; Olson, Krista F. ; Kelly, Susan ; Beattie, Charles. / Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events : A randomized clinical trial. In: Journal of the American Medical Association. 1997 ; Vol. 277, No. 14. pp. 1127-1134.
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