Perioperative Anticoagulant Management

Paul J. Grant, Daniel Brotman, Amir K. Jaffer

Research output: Contribution to journalArticle

Abstract

The oral anticoagulant warfarin is a common medication that requires special consideration in the perioperative period. Although some procedures do not require warfarin interruption, the majority will necessitate its temporary cessation due to the risk of bleeding. Determining whether patients will benefit from the temporary use of a heparin product while warfarin is discontinued perioperatively (so-called "bridging" therapy) needs to take into consideration the risk of bleeding balanced with the risk of thromboembolism. Perioperative care also requires minimizing the risk of venous thromboembolism (VTE). Understanding the patient-specific and procedure-specific risks for VTE is paramount to employ optimal risk reduction strategies. This article uses a case-based approach to present the topics of perioperative warfarin management and postoperative VTE prevention.

Original languageEnglish (US)
Pages (from-to)761-777
Number of pages17
JournalAnesthesiology Clinics
Volume27
Issue number4
DOIs
StatePublished - Dec 2009

Fingerprint

Anticoagulants
Warfarin
Venous Thromboembolism
Hemorrhage
Perioperative Care
Perioperative Period
Thromboembolism
Risk Reduction Behavior
Heparin
Therapeutics

Keywords

  • Anticoagulation
  • Heparin
  • Perioperative care
  • Risk factors
  • Venous thromboembolism
  • Warfarin

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Perioperative Anticoagulant Management. / Grant, Paul J.; Brotman, Daniel; Jaffer, Amir K.

In: Anesthesiology Clinics, Vol. 27, No. 4, 12.2009, p. 761-777.

Research output: Contribution to journalArticle

Grant, Paul J. ; Brotman, Daniel ; Jaffer, Amir K. / Perioperative Anticoagulant Management. In: Anesthesiology Clinics. 2009 ; Vol. 27, No. 4. pp. 761-777.
@article{554e765a824a44568eacda0bd24270a2,
title = "Perioperative Anticoagulant Management",
abstract = "The oral anticoagulant warfarin is a common medication that requires special consideration in the perioperative period. Although some procedures do not require warfarin interruption, the majority will necessitate its temporary cessation due to the risk of bleeding. Determining whether patients will benefit from the temporary use of a heparin product while warfarin is discontinued perioperatively (so-called {"}bridging{"} therapy) needs to take into consideration the risk of bleeding balanced with the risk of thromboembolism. Perioperative care also requires minimizing the risk of venous thromboembolism (VTE). Understanding the patient-specific and procedure-specific risks for VTE is paramount to employ optimal risk reduction strategies. This article uses a case-based approach to present the topics of perioperative warfarin management and postoperative VTE prevention.",
keywords = "Anticoagulation, Heparin, Perioperative care, Risk factors, Venous thromboembolism, Warfarin",
author = "Grant, {Paul J.} and Daniel Brotman and Jaffer, {Amir K.}",
year = "2009",
month = "12",
doi = "10.1016/j.anclin.2009.09.010",
language = "English (US)",
volume = "27",
pages = "761--777",
journal = "Anesthesiology Clinics",
issn = "1932-2275",
publisher = "W.B. Saunders Ltd",
number = "4",

}

TY - JOUR

T1 - Perioperative Anticoagulant Management

AU - Grant, Paul J.

AU - Brotman, Daniel

AU - Jaffer, Amir K.

PY - 2009/12

Y1 - 2009/12

N2 - The oral anticoagulant warfarin is a common medication that requires special consideration in the perioperative period. Although some procedures do not require warfarin interruption, the majority will necessitate its temporary cessation due to the risk of bleeding. Determining whether patients will benefit from the temporary use of a heparin product while warfarin is discontinued perioperatively (so-called "bridging" therapy) needs to take into consideration the risk of bleeding balanced with the risk of thromboembolism. Perioperative care also requires minimizing the risk of venous thromboembolism (VTE). Understanding the patient-specific and procedure-specific risks for VTE is paramount to employ optimal risk reduction strategies. This article uses a case-based approach to present the topics of perioperative warfarin management and postoperative VTE prevention.

AB - The oral anticoagulant warfarin is a common medication that requires special consideration in the perioperative period. Although some procedures do not require warfarin interruption, the majority will necessitate its temporary cessation due to the risk of bleeding. Determining whether patients will benefit from the temporary use of a heparin product while warfarin is discontinued perioperatively (so-called "bridging" therapy) needs to take into consideration the risk of bleeding balanced with the risk of thromboembolism. Perioperative care also requires minimizing the risk of venous thromboembolism (VTE). Understanding the patient-specific and procedure-specific risks for VTE is paramount to employ optimal risk reduction strategies. This article uses a case-based approach to present the topics of perioperative warfarin management and postoperative VTE prevention.

KW - Anticoagulation

KW - Heparin

KW - Perioperative care

KW - Risk factors

KW - Venous thromboembolism

KW - Warfarin

UR - http://www.scopus.com/inward/record.url?scp=70449727105&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70449727105&partnerID=8YFLogxK

U2 - 10.1016/j.anclin.2009.09.010

DO - 10.1016/j.anclin.2009.09.010

M3 - Article

C2 - 19942179

AN - SCOPUS:70449727105

VL - 27

SP - 761

EP - 777

JO - Anesthesiology Clinics

JF - Anesthesiology Clinics

SN - 1932-2275

IS - 4

ER -