Perineural spread of melanoma demonstrated by F-18 FDG PET with MRI and pathologic correlation

Theodore J. Lee; Christine M. Glastonbury; Anne F. Buckley; David W. Eisele; Randall A. Hawkins

doi:10.1097/RLU.0b013e31815ef7be

Perineural spread of melanoma demonstrated by F-18 FDG PET with MRI and pathologic correlation

Theodore J. Lee, Christine M. Glastonbury, Anne F. Buckley, David W. Eisele, Randall A. Hawkins

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

F-18 FDG-PET is generally considered insensitive for the detection of perineural tumor spread. A case is presented of abnormal linear tracer uptake corresponding to the body of the right mandible on a PET scan in a patient with a history of lip melanoma. MRI correlation showed abnormal enlargement and enhancement of the intramandibular portion of the right inferior alveolar nerve. Surgical resection with pathologic analysis confirmed perineural spread of spindle cell melanoma of the lip. Perineural tumor should be considered when asymmetric linear radiotracer uptake is seen on PET scans of the head and neck that does not correspond to the anatomic course of muscular structures.

Original language	English (US)
Pages (from-to)	106-108
Number of pages	3
Journal	Clinical nuclear medicine
Volume	33
Issue number	2
DOIs	https://doi.org/10.1097/RLU.0b013e31815ef7be
State	Published - Feb 2008
Externally published	Yes

Keywords

FDG-PET
Melanoma
Perineural tumor
Trigeminal nerve

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/RLU.0b013e31815ef7be

Cite this

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title = "Perineural spread of melanoma demonstrated by F-18 FDG PET with MRI and pathologic correlation",

abstract = "F-18 FDG-PET is generally considered insensitive for the detection of perineural tumor spread. A case is presented of abnormal linear tracer uptake corresponding to the body of the right mandible on a PET scan in a patient with a history of lip melanoma. MRI correlation showed abnormal enlargement and enhancement of the intramandibular portion of the right inferior alveolar nerve. Surgical resection with pathologic analysis confirmed perineural spread of spindle cell melanoma of the lip. Perineural tumor should be considered when asymmetric linear radiotracer uptake is seen on PET scans of the head and neck that does not correspond to the anatomic course of muscular structures.",

keywords = "FDG-PET, Melanoma, Perineural tumor, Trigeminal nerve",

author = "Lee, {Theodore J.} and Glastonbury, {Christine M.} and Buckley, {Anne F.} and Eisele, {David W.} and Hawkins, {Randall A.}",

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T1 - Perineural spread of melanoma demonstrated by F-18 FDG PET with MRI and pathologic correlation

AU - Lee, Theodore J.

AU - Glastonbury, Christine M.

AU - Buckley, Anne F.

AU - Eisele, David W.

AU - Hawkins, Randall A.

PY - 2008/2

Y1 - 2008/2

N2 - F-18 FDG-PET is generally considered insensitive for the detection of perineural tumor spread. A case is presented of abnormal linear tracer uptake corresponding to the body of the right mandible on a PET scan in a patient with a history of lip melanoma. MRI correlation showed abnormal enlargement and enhancement of the intramandibular portion of the right inferior alveolar nerve. Surgical resection with pathologic analysis confirmed perineural spread of spindle cell melanoma of the lip. Perineural tumor should be considered when asymmetric linear radiotracer uptake is seen on PET scans of the head and neck that does not correspond to the anatomic course of muscular structures.

AB - F-18 FDG-PET is generally considered insensitive for the detection of perineural tumor spread. A case is presented of abnormal linear tracer uptake corresponding to the body of the right mandible on a PET scan in a patient with a history of lip melanoma. MRI correlation showed abnormal enlargement and enhancement of the intramandibular portion of the right inferior alveolar nerve. Surgical resection with pathologic analysis confirmed perineural spread of spindle cell melanoma of the lip. Perineural tumor should be considered when asymmetric linear radiotracer uptake is seen on PET scans of the head and neck that does not correspond to the anatomic course of muscular structures.

KW - FDG-PET

KW - Melanoma

KW - Perineural tumor

KW - Trigeminal nerve

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Perineural spread of melanoma demonstrated by F-18 FDG PET with MRI and pathologic correlation

Abstract

Keywords

ASJC Scopus subject areas

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