Gliomatose aracnoidal perineural: Relato de caso

Translated title of the contribution: Perineural arachnoidal gliomatosis: Case report

Luciano Sousa Pereira, Timothy James McCulley

Research output: Contribution to journalArticlepeer-review

Abstract

Gliomas are the most common infiltrative neoplasms of the optic nerve and can present as two distinct growth patterns: intraneural glial proliferation and perineural arachnoidal gliomatosis (PAG). It has been suggested that perineural arachnoidal gliomatosis is seen almost exclusively in the setting of neurofibromatosis type 1 (NF1). We describe a child with perineural arachnoidal gliomatosis occurring without neurofibromatosis type 1, supported by both radiographic and histological findings. A 4-year-old female without neurofibromatosis type 1 presented with rapidly progressive rightsided proptosis. Magnetic resonance imaging (MRI) revealed an enhancing fusiform intraconal lesion, which was hypointense on T1 and hyperintense on T2-weighted images: characteristic of perineural arachnoidal gliomatosis, the optic nerve was visualized coursing the tumor. Histopathologic study was consistent with perineural arachnoidal gliomatosis. Perineural arachnoidal gliomatosis can develop independent of neurofibromatosis type 1, as demonstrated by this case.

Translated title of the contributionPerineural arachnoidal gliomatosis: Case report
Original languagePortuguese
Pages (from-to)595-598
Number of pages4
JournalArquivos brasileiros de oftalmologia
Volume71
Issue number4
DOIs
StatePublished - Jan 2008
Externally publishedYes

Keywords

  • Case reports [Publication type]
  • Child
  • Female
  • Human
  • Magnetic resonance imaging
  • Neurofibromatosis/pathology
  • Optic nerve glioma

ASJC Scopus subject areas

  • Ophthalmology

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