Performance of the cryptococcal antigen lateral flow assay in non-HIV-related cryptococcosis

Anupop Jitmuang; Anil A. Panackal; Peter R. Williamson; John E. Bennett; John P. Dekker; Adrian M. Zelazny

doi:10.1128/JCM.02223-15

Performance of the cryptococcal antigen lateral flow assay in non-HIV-related cryptococcosis

Anupop Jitmuang, Anil A. Panackal, Peter R. Williamson, John E. Bennett, John P. Dekker, Adrian M. Zelazny

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.

Original language	English (US)
Pages (from-to)	460-463
Number of pages	4
Journal	Journal of clinical microbiology
Volume	54
Issue number	2
DOIs	https://doi.org/10.1128/JCM.02223-15
State	Published - Feb 2016

ASJC Scopus subject areas

Microbiology (medical)

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abstract = "The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.",

author = "Anupop Jitmuang and Panackal, {Anil A.} and Williamson, {Peter R.} and Bennett, {John E.} and Dekker, {John P.} and Zelazny, {Adrian M.}",

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AU - Dekker, John P.

AU - Zelazny, Adrian M.

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AB - The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.

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Performance of the cryptococcal antigen lateral flow assay in non-HIV-related cryptococcosis

Abstract

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