Performance of the ABCD and ABCD2 scores in TIA patients with carotid stenosis and atrial fibrillation

S. Koton, P. M. Rothwell

Research output: Contribution to journalArticle

Abstract

Background: It has been suggested that scores for risk stratification of TIA patients might not identify patients with carotid stenosis or atrial fibrillation (AF) and that this might undermine the usefulness of such scores. Methods: In patients with TIA in the Oxford Vascular Study, we studied the associations between ABCD and ABCD2 scores, the presence of ≥50% ipsilateral carotid stenosis or AF, and the risk of stroke at 7 days. Results: Among 285 TIA patients (from 559 referrals of possible TIA), 69 (24.2%) had either ≥50% carotid stenosis (n = 29) or AF (n = 42), or both (n = 2). Although the ABCD and ABCD2 scores were highly predictive of stroke at 7 days (p <0.0001), there was no clear relationship between either score and the prevalence of ≥50% carotid stenosis or AF. However, the scores did predict the 7-day stroke risk in patients with these pathologies: ABCD score (trend - p = 0.05); ABCD2 (trend - p = 0.03). Five of the 6 patients with AF or symptomatic stenosis who had a stroke within 7 days of their TIA had an ABCD score of ≥5 and all 6 had an ABCD2 score of ≥4. Conclusions: The ABCD and ABCD2 risk scores appear to identify patients with ≥50% carotid stenosis or AF who are at high risk of stroke. However, these findings should be interpreted with caution due to the small number of outcomes among these subgroups, and further validations are necessary.

Original languageEnglish (US)
Pages (from-to)231-235
Number of pages5
JournalCerebrovascular Diseases
Volume24
Issue number2-3
DOIs
StatePublished - Aug 2007
Externally publishedYes

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Carotid Stenosis
Atrial Fibrillation
Stroke
Blood Vessels
Pathologic Constriction
Referral and Consultation
Pathology

Keywords

  • ABCD score
  • ABCD2 score
  • Atrial fibrillation
  • Carotid stenosis
  • Stroke risk
  • Transient ischemic attack

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Performance of the ABCD and ABCD2 scores in TIA patients with carotid stenosis and atrial fibrillation. / Koton, S.; Rothwell, P. M.

In: Cerebrovascular Diseases, Vol. 24, No. 2-3, 08.2007, p. 231-235.

Research output: Contribution to journalArticle

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