Performance of speech perception after cochlear implantation in DFNB1 patients

Viviana Dalamón, Vanesa Lotersztein, Marcela Lipovsek, Agustina Béhern, Maria Elena Mondino, Fernando Diamante, Norma Pallares, Vicente Diamante, Ana Belen Elgoyhen

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Conclusion: There were no apparent differences in speech performance after cochlear implantation between patients with biallelic GJB2 and/or GJB6 mutations and those with deafness of unknown aetiology. These data have important implications for the selection of prognostic indicators of the outcome of cochlear implantation. Objective: To compare performance after cochlear implantation in children with mutations in GJB2 (connexin 26) and/or GJB6 (connexin 30) and children with deafness of unknown aetiology. Subjects and methods: Genetic analysis and speech performance evaluation was determined in 24 patients with (n=11) and without (n=13) biallelic GJB2 and/or GJB6 mutations who underwent cochlear implantation. Speech perception skills were measured 12 and 24 months after surgery. Each patient was classified in accordance with the speech perception category (SPC). Results: Overall, the two groups showed similar significant improvement in speech perception after implantation.

Original languageEnglish (US)
Pages (from-to)395-398
Number of pages4
JournalActa Oto-Laryngologica
Issue number4
StatePublished - 2009
Externally publishedYes


  • Cochlear implant
  • Connexin 26
  • Connexin 30
  • Deafness
  • GJB2
  • GJB6
  • Hearing loss
  • Speech perception

ASJC Scopus subject areas

  • Otorhinolaryngology


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