Performance of a new enzyme-linked immunoassay urine pregnancy test for the detection of ectopic gestation

Peter S. Cartwright; Deborah F. Victory; Royanne A. Moore; Jean R. Anderson; Douglas H. Brown

doi:10.1016/S0196-0644(86)80865-4

Performance of a new enzyme-linked immunoassay urine pregnancy test for the detection of ectopic gestation

Peter S. Cartwright, Deborah F. Victory, Royanne A. Moore, Jean R. Anderson, Douglas H. Brown

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

An enzyme-linked immunoassay urine pregnancy test was used on a group of patients suspected of having an ectopic pregnancy. Patients were seen in the county hospital emergency department and had the urine test correlated with a serum β-hCG level determined by radioimmunoassay. There were 884 patients with urine ICON-serum β-hCG correlations. The ICON was positive in each of the 247 patients whose serum value was over 50 mIU/mL, and was negative in each of the 619 patients whose serum level was below 5 mIU/mL. Eighteen patients had a serum level between 10 and 50 mIU/mL and the ICON was positive in 13. The five patients with a low serum β-hCG level and a negative ICON had dilute urine when tested. Using a modified testing procedure, each of these produced a positive ICON. Of the 27 patients with an ectopic pregnancy the urine ICON was positive in 26. The urine ICON is an improved assay for hCG in patients suspected of having an ectopic pregnancy, and is ideally suited for ED use.

Original language	English (US)
Pages (from-to)	1198-1199
Number of pages	2
Journal	Annals of emergency medicine
Volume	15
Issue number	10
DOIs	https://doi.org/10.1016/S0196-0644(86)80865-4
State	Published - Oct 1986
Externally published	Yes

Keywords

ectopic pregnancy, detection
pregnancy, ectopic, detection
testing, ectopic pregnancy, enzyme-linked immunoassay

ASJC Scopus subject areas

Emergency Medicine

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10.1016/S0196-0644(86)80865-4

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title = "Performance of a new enzyme-linked immunoassay urine pregnancy test for the detection of ectopic gestation",

abstract = "An enzyme-linked immunoassay urine pregnancy test was used on a group of patients suspected of having an ectopic pregnancy. Patients were seen in the county hospital emergency department and had the urine test correlated with a serum β-hCG level determined by radioimmunoassay. There were 884 patients with urine ICON-serum β-hCG correlations. The ICON was positive in each of the 247 patients whose serum value was over 50 mIU/mL, and was negative in each of the 619 patients whose serum level was below 5 mIU/mL. Eighteen patients had a serum level between 10 and 50 mIU/mL and the ICON was positive in 13. The five patients with a low serum β-hCG level and a negative ICON had dilute urine when tested. Using a modified testing procedure, each of these produced a positive ICON. Of the 27 patients with an ectopic pregnancy the urine ICON was positive in 26. The urine ICON is an improved assay for hCG in patients suspected of having an ectopic pregnancy, and is ideally suited for ED use.",

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author = "Cartwright, {Peter S.} and Victory, {Deborah F.} and Moore, {Royanne A.} and Anderson, {Jean R.} and Brown, {Douglas H.}",

year = "1986",

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AU - Brown, Douglas H.

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KW - testing, ectopic pregnancy, enzyme-linked immunoassay

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Performance of a new enzyme-linked immunoassay urine pregnancy test for the detection of ectopic gestation

Abstract

Keywords

ASJC Scopus subject areas

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