Performance of a new enzyme-linked immunoassay urine pregnancy test for the detection of ectopic gestation

Peter S. Cartwright, Deborah F. Victory, Royanne A. Moore, Jean Anderson, Douglas H. Brown

Research output: Contribution to journalArticle

Abstract

An enzyme-linked immunoassay urine pregnancy test was used on a group of patients suspected of having an ectopic pregnancy. Patients were seen in the county hospital emergency department and had the urine test correlated with a serum β-hCG level determined by radioimmunoassay. There were 884 patients with urine ICON-serum β-hCG correlations. The ICON was positive in each of the 247 patients whose serum value was over 50 mIU/mL, and was negative in each of the 619 patients whose serum level was below 5 mIU/mL. Eighteen patients had a serum level between 10 and 50 mIU/mL and the ICON was positive in 13. The five patients with a low serum β-hCG level and a negative ICON had dilute urine when tested. Using a modified testing procedure, each of these produced a positive ICON. Of the 27 patients with an ectopic pregnancy the urine ICON was positive in 26. The urine ICON is an improved assay for hCG in patients suspected of having an ectopic pregnancy, and is ideally suited for ED use.

Original languageEnglish (US)
Pages (from-to)1198-1199
Number of pages2
JournalAnnals of Emergency Medicine
Volume15
Issue number10
DOIs
Publication statusPublished - 1986
Externally publishedYes

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Keywords

  • ectopic pregnancy, detection
  • pregnancy, ectopic, detection
  • testing, ectopic pregnancy, enzyme-linked immunoassay

ASJC Scopus subject areas

  • Emergency Medicine

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