Performance-based and parent ratings of attention in children treated for a brain tumor: The significance of radiation therapy and tumor location on outcome

Kimberly P. Raghubar, E. Mark Mahone, Keith Owen Yeates, M. Douglas Ris

Research output: Contribution to journalArticle

Abstract

Children are at increased risk for cognitive difficulties following the diagnosis and treatment of a brain tumor. Radiation therapy (RT) and tumor location are commonly-cited predictors of neurocognitive functioning. Disruptions to foundational neurocognitive processes such as attention, working memory, and processing speed underlie declines on measures of general intellectual functioning. While several studies have examined visual sustained attention in pediatric brain tumor patients, auditory sustained attention has yet to be examined. This study employs a longitudinal design to examine performance-based and parent ratings of attention in children undergoing surgical resection of a brain tumor (n = 29) and treated with (n = 11) or without (n = 18) RT at 6.79 months post-surgery (baseline) and then again at 30.56 months post-surgery (follow-up). The measures include an auditory continuous performance test (CPT) and parent ratings of attention and hyperactivity on a behavior rating scale. Ultimately, children treated with and without RT performed similarly on performance-based and parent ratings of attention. However, the performance on the auditory CPT differed according to tumor location, with children with infratentorial tumors committing more inattention and inhibitory control errors compared to children with supratentorial tumors. Parent ratings did not differ according to tumor location, and parent ratings and auditory sustained attention performance are not significantly correlated. The findings are interpreted in the context of neurocognitive and brain development.

Original languageEnglish (US)
Pages (from-to)1-13
Number of pages13
JournalChild Neuropsychology
DOIs
StateAccepted/In press - Jan 28 2017

Fingerprint

Brain Neoplasms
Radiation
Neoplasms
Supratentorial Neoplasms
Infratentorial Neoplasms
Short-Term Memory
Pediatrics
Brain

Keywords

  • Brain tumor
  • Pediatric
  • Radiation
  • Sustained attention
  • Tumor location

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neuropsychology and Physiological Psychology
  • Medicine(all)
  • Developmental and Educational Psychology

Cite this

Performance-based and parent ratings of attention in children treated for a brain tumor : The significance of radiation therapy and tumor location on outcome. / Raghubar, Kimberly P.; Mahone, E. Mark; Yeates, Keith Owen; Ris, M. Douglas.

In: Child Neuropsychology, 28.01.2017, p. 1-13.

Research output: Contribution to journalArticle

Raghubar, Kimberly P.; Mahone, E. Mark; Yeates, Keith Owen; Ris, M. Douglas / Performance-based and parent ratings of attention in children treated for a brain tumor : The significance of radiation therapy and tumor location on outcome.

In: Child Neuropsychology, 28.01.2017, p. 1-13.

Research output: Contribution to journalArticle

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