Penile transplantation: An emerging option for genitourinary reconstruction

Research output: Research - peer-reviewArticle

Abstract

Penile transplantation is an emerging option for patients with severe genital defects not amenable to traditional reconstructive options. In this article, we discuss the burgeoning problem of severe male genitourinary trauma in the military, the limitations of traditional reconstructive options in addressing these problems, and the potential for penile transplantation to provide improved outcomes. We also review the preclinical research and limited worldwide experience with penile transplantation to date, including lessons learned, and discuss the many important technical, logistical, and ethical considerations pertaining to penile transplantation that must be addressed to maximize the likelihood of successful implementation.

LanguageEnglish (US)
JournalTransplant International
DOIs
StateAccepted/In press - 2017

Fingerprint

Transplantation
Wounds and Injuries
Research

Keywords

  • Penile defects
  • Penile transplant
  • Reconstructive surgical procedures
  • Vascularized composite allotransplantation

ASJC Scopus subject areas

  • Transplantation

Cite this

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title = "Penile transplantation: An emerging option for genitourinary reconstruction",
abstract = "Penile transplantation is an emerging option for patients with severe genital defects not amenable to traditional reconstructive options. In this article, we discuss the burgeoning problem of severe male genitourinary trauma in the military, the limitations of traditional reconstructive options in addressing these problems, and the potential for penile transplantation to provide improved outcomes. We also review the preclinical research and limited worldwide experience with penile transplantation to date, including lessons learned, and discuss the many important technical, logistical, and ethical considerations pertaining to penile transplantation that must be addressed to maximize the likelihood of successful implementation.",
keywords = "Penile defects, Penile transplant, Reconstructive surgical procedures, Vascularized composite allotransplantation",
author = "Tuffaha, {Sami H.} and Cooney, {Damon S.} and Sopko, {Nikolai A.} and Bivalacqua, {Trinity J.} and Lough, {Denver M.} and Cooney, {Carisa M.} and Gerald Brandacher and Lee, {Wei Ping Andrew} and Burnett, {Arthur L.} and Redett, {Richard J.}",
year = "2017",
doi = "10.1111/tri.12928",
journal = "Transplant International",
issn = "0934-0874",
publisher = "Wiley-Blackwell",

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T2 - Transplant International

AU - Tuffaha,Sami H.

AU - Cooney,Damon S.

AU - Sopko,Nikolai A.

AU - Bivalacqua,Trinity J.

AU - Lough,Denver M.

AU - Cooney,Carisa M.

AU - Brandacher,Gerald

AU - Lee,Wei Ping Andrew

AU - Burnett,Arthur L.

AU - Redett,Richard J.

PY - 2017

Y1 - 2017

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AB - Penile transplantation is an emerging option for patients with severe genital defects not amenable to traditional reconstructive options. In this article, we discuss the burgeoning problem of severe male genitourinary trauma in the military, the limitations of traditional reconstructive options in addressing these problems, and the potential for penile transplantation to provide improved outcomes. We also review the preclinical research and limited worldwide experience with penile transplantation to date, including lessons learned, and discuss the many important technical, logistical, and ethical considerations pertaining to penile transplantation that must be addressed to maximize the likelihood of successful implementation.

KW - Penile defects

KW - Penile transplant

KW - Reconstructive surgical procedures

KW - Vascularized composite allotransplantation

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