Pelvic pain and surgeries in women before interstitial cystitis/painful bladder syndrome

Patricia W. Langenberg, Edward E Wallach, Daniel J. Clauw, Fred M. Howard, Christina M. Diggs, Ursula Wesselmann, Patty Greenberg, John W. Warren

Research output: Contribution to journalArticle

Abstract

Objective: The objective of the study was to compare subjects with interstitial cystitis/painful bladder syndrome (IC/PBS) with controls on prior surgeries. Study Design: IC/PBS subjects were compared with matched controls on surgeries and possible surgical indications prior to their index dates. Results: Adjusted for demographic variables, logistic regression showed subjects exceeded controls in surgeries longer than 12 months and less than 1 month before the index date. However, addition of possible surgical indications showed chronic pelvic pain (CPP) to have a strong association with IC/PBS, whereas associations with surgeries were reduced to nonsignificance. Conclusion: Although women with IC/PBS were more likely to have experienced prior surgeries than controls, the apparent indications for surgeries, not the surgeries themselves, were stronger risk factors for IC/PBS. In particular, a prior history of CPP had a strong association with IC/PBS. Several features of study design, including extensive medical record review, suggest that prior CPP was not undiagnosed IC/PBS. Further investigation of CPP may yield insight into the pathogenesis of IC/PBS.

Original languageEnglish (US)
JournalAmerican Journal of Obstetrics and Gynecology
Volume202
Issue number3
DOIs
StatePublished - Mar 2010

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Interstitial Cystitis
Pelvic Pain
Chronic Pain

Keywords

  • chronic pelvic pain
  • fibromyalgia
  • hysterectomy
  • interstitial cystitis
  • oophorectomy
  • risk factor

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Pelvic pain and surgeries in women before interstitial cystitis/painful bladder syndrome. / Langenberg, Patricia W.; Wallach, Edward E; Clauw, Daniel J.; Howard, Fred M.; Diggs, Christina M.; Wesselmann, Ursula; Greenberg, Patty; Warren, John W.

In: American Journal of Obstetrics and Gynecology, Vol. 202, No. 3, 03.2010.

Research output: Contribution to journalArticle

Langenberg, Patricia W. ; Wallach, Edward E ; Clauw, Daniel J. ; Howard, Fred M. ; Diggs, Christina M. ; Wesselmann, Ursula ; Greenberg, Patty ; Warren, John W. / Pelvic pain and surgeries in women before interstitial cystitis/painful bladder syndrome. In: American Journal of Obstetrics and Gynecology. 2010 ; Vol. 202, No. 3.
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