Pelvic normal tissue contouring guidelines for radiation therapy: A radiation therapy oncology group consensus panel atlas

Hiram A. Gay, H. Joseph Barthold, Elizabeth O'Meara, Walter R. Bosch, Issam El Naqa, Rawan Al-Lozi, Seth A. Rosenthal, Colleen Lawton, W. Robert Lee, Howard Sandler, Anthony Zietman, Robert Myerson, Laura A. Dawson, Christopher Willett, Lisa A. Kachnic, Anuja Jhingran, Lorraine Portelance, Janice Ryu, William Small, David GaffneyAkila Viswanathan, Jeff M. Michalski

Research output: Contribution to journalArticle

Abstract

Purpose: To define a male and female pelvic normal tissue contouring atlas for Radiation Therapy Oncology Group (RTOG) trials. Methods and Materials: One male pelvis computed tomography (CT) data set and one female pelvis CT data set were shared via the Image-Guided Therapy QA Center. A total of 16 radiation oncologists participated. The following organs at risk were contoured in both CT sets: anus, anorectum, rectum (gastrointestinal and genitourinary definitions), bowel NOS (not otherwise specified), small bowel, large bowel, and proximal femurs. The following were contoured in the male set only: bladder, prostate, seminal vesicles, and penile bulb. The following were contoured in the female set only: uterus, cervix, and ovaries. A computer program used the binomial distribution to generate 95% group consensus contours. These contours and definitions were then reviewed by the group and modified. Results: The panel achieved consensus definitions for pelvic normal tissue contouring in RTOG trials with these standardized names: Rectum, AnoRectum, SmallBowel, Colon, BowelBag, Bladder, UteroCervix, Adnexa-R, Adnexa-L, Prostate, SeminalVesc, PenileBulb, Femur-R, and Femur-L. Two additional normal structures whose purpose is to serve as targets in anal and rectal cancer were defined: AnoRectumSig and Mesorectum. Detailed target volume contouring guidelines and images are discussed. Conclusions: Consensus guidelines for pelvic normal tissue contouring were reached and are available as a CT image atlas on the RTOG Web site. This will allow uniformity in defining normal tissues for clinical trials delivering pelvic radiation and will facilitate future normal tissue complication research.

Original languageEnglish (US)
JournalInternational Journal of Radiation Oncology Biology Physics
Volume83
Issue number3
DOIs
StatePublished - Jul 1 2012
Externally publishedYes

Fingerprint

Radiation Oncology
Atlases
radiation therapy
Radiotherapy
femur
Guidelines
tomography
Tomography
Femur
rectum
pelvis
bladder
Pelvis
Rectum
Prostate
Urinary Bladder
Binomial Distribution
Anus Neoplasms
Organs at Risk
uterus

Keywords

  • Female pelvis
  • Male pelvis
  • Normal tissue volumes
  • Pelvic contouring atlas
  • Radiation therapy atlas

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiation
  • Cancer Research

Cite this

Pelvic normal tissue contouring guidelines for radiation therapy : A radiation therapy oncology group consensus panel atlas. / Gay, Hiram A.; Barthold, H. Joseph; O'Meara, Elizabeth; Bosch, Walter R.; El Naqa, Issam; Al-Lozi, Rawan; Rosenthal, Seth A.; Lawton, Colleen; Lee, W. Robert; Sandler, Howard; Zietman, Anthony; Myerson, Robert; Dawson, Laura A.; Willett, Christopher; Kachnic, Lisa A.; Jhingran, Anuja; Portelance, Lorraine; Ryu, Janice; Small, William; Gaffney, David; Viswanathan, Akila; Michalski, Jeff M.

In: International Journal of Radiation Oncology Biology Physics, Vol. 83, No. 3, 01.07.2012.

Research output: Contribution to journalArticle

Gay, HA, Barthold, HJ, O'Meara, E, Bosch, WR, El Naqa, I, Al-Lozi, R, Rosenthal, SA, Lawton, C, Lee, WR, Sandler, H, Zietman, A, Myerson, R, Dawson, LA, Willett, C, Kachnic, LA, Jhingran, A, Portelance, L, Ryu, J, Small, W, Gaffney, D, Viswanathan, A & Michalski, JM 2012, 'Pelvic normal tissue contouring guidelines for radiation therapy: A radiation therapy oncology group consensus panel atlas', International Journal of Radiation Oncology Biology Physics, vol. 83, no. 3. https://doi.org/10.1016/j.ijrobp.2012.01.023
Gay, Hiram A. ; Barthold, H. Joseph ; O'Meara, Elizabeth ; Bosch, Walter R. ; El Naqa, Issam ; Al-Lozi, Rawan ; Rosenthal, Seth A. ; Lawton, Colleen ; Lee, W. Robert ; Sandler, Howard ; Zietman, Anthony ; Myerson, Robert ; Dawson, Laura A. ; Willett, Christopher ; Kachnic, Lisa A. ; Jhingran, Anuja ; Portelance, Lorraine ; Ryu, Janice ; Small, William ; Gaffney, David ; Viswanathan, Akila ; Michalski, Jeff M. / Pelvic normal tissue contouring guidelines for radiation therapy : A radiation therapy oncology group consensus panel atlas. In: International Journal of Radiation Oncology Biology Physics. 2012 ; Vol. 83, No. 3.
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AU - Bosch, Walter R.

AU - El Naqa, Issam

AU - Al-Lozi, Rawan

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AU - Lee, W. Robert

AU - Sandler, Howard

AU - Zietman, Anthony

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AU - Dawson, Laura A.

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AU - Portelance, Lorraine

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