Abstract
Twenty-one families with familial Alzheimer disease were ascertained in a dementia clinic and assessed by multiple family interviews. Eight autopsies were reviewed. The age of onset varied from 25 to 85. Seven pedigrees showed evidence of 3 generation transmission. Paternal age of the founders of 4 lines which could be assessed was higher than controls.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 189-197 |
| Number of pages | 9 |
| Journal | Journal of Neurogenetics |
| Volume | 1 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1984 |
Keywords
- Alzheimer disease
- Pedigree study
ASJC Scopus subject areas
- Genetics
- Cellular and Molecular Neuroscience
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Cite this
Powell, D., & Folstein, M. F. (1984). Pedigree study of familial alzheimer disease. Journal of Neurogenetics, 1(2), 189-197. https://doi.org/10.3109/01677068409107085