Abstract
Twenty-one families with familial Alzheimer disease were ascertained in a dementia clinic and assessed by multiple family interviews. Eight autopsies were reviewed. The age of onset varied from 25 to 85. Seven pedigrees showed evidence of 3 generation transmission. Paternal age of the founders of 4 lines which could be assessed was higher than controls.
Original language | English (US) |
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Pages (from-to) | 189-197 |
Number of pages | 9 |
Journal | Journal of Neurogenetics |
Volume | 1 |
Issue number | 2 |
DOIs | |
State | Published - 1984 |
Keywords
- Alzheimer disease
- Pedigree study
ASJC Scopus subject areas
- Genetics
- Cellular and Molecular Neuroscience