TY - JOUR
T1 - Pediatric testicular tumors
T2 - The Johns Hopkins experience
AU - Leonard, Michael P.
AU - Jeffs, Robert D.
AU - Leventhal, Brigid
AU - Gearhart, John P.
PY - 1991/3
Y1 - 1991/3
N2 - Testicular neoplasms constitute 1 percent of all childhood malignancies and rankeighth in childhood cancer mortality. From 1970 to 1988, 25 testicular tumors in children eighteen years and under were seen. The majority of the patients were white (88 %). Pathologic analysis of the tumors revealed that 68 percent were germinal and 32 percent were nongerminal. Staging was undertaken in all patients with serum markers, chest x-ray film, and computerized tomography scans or lymphangiography. All patients underwent radical orchiectomy, and further therapy was given dependent on tumor type and stage. The survival among this cohort was excellent, with only 3 patients succumbing to their disease. Detailed results of treatment, and approaches to avoid excess treatment morbidity are reviewed.
AB - Testicular neoplasms constitute 1 percent of all childhood malignancies and rankeighth in childhood cancer mortality. From 1970 to 1988, 25 testicular tumors in children eighteen years and under were seen. The majority of the patients were white (88 %). Pathologic analysis of the tumors revealed that 68 percent were germinal and 32 percent were nongerminal. Staging was undertaken in all patients with serum markers, chest x-ray film, and computerized tomography scans or lymphangiography. All patients underwent radical orchiectomy, and further therapy was given dependent on tumor type and stage. The survival among this cohort was excellent, with only 3 patients succumbing to their disease. Detailed results of treatment, and approaches to avoid excess treatment morbidity are reviewed.
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U2 - 10.1016/0090-4295(91)80297-K
DO - 10.1016/0090-4295(91)80297-K
M3 - Article
C2 - 2000685
AN - SCOPUS:0026036019
SN - 0090-4295
VL - 37
SP - 253
EP - 256
JO - Urology
JF - Urology
IS - 3
ER -