Pediatric research ethics: Evolving principles and practices

Research output: Contribution to journalShort surveypeer-review


In contrast to a historical prohibition against research involving children, there is a current emphasis on enhancing children's access to research to prevent and treat pediatric disease. Healthy children may not participate in research protocols entailing more than minimal risk. Sick children may be permitted to participate in protocols involving slightly more risk, if they may receive direct benefit or if vital information about their disorder can be gathered. As the number of pediatric research participants increases, there must be a commitment to providing the local, national, and international oversight and resources necessary to maximize safety. Pediatricians, researchers, IRBs, and parents must work together to refine and apply the principles of respect for persons, justice, and beneficence to children.

Original languageEnglish (US)
Pages (from-to)163-165
Number of pages3
JournalPediatrics in review
Issue number4
StatePublished - Apr 2010

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Pediatric research ethics: Evolving principles and practices'. Together they form a unique fingerprint.

Cite this