Pediatric littoral cell angioma of the spleen: Multimodality imaging including diffusion-weighted imaging

Gulhan Ertan, Aylin Tekes, Sally E Mitchell, Jeffrey Keefer, Thierry A G M Huisman

Research output: Contribution to journalArticle


Littoral cell angioma (LCA) is a rare primary splenic vascular tumor originating from littoral cells lining the splenic red pulp sinuses. LCAs are rarely seen in children. We present the US, CT, and MRI findings including diffusion-weighted imaging (DWI) in a 2-year-old boy with histologically proven LCA. Previous studies on liver lesions have shown that DWI allows differentiation of vascular tumors from primary neoplasms and metastatic disease. The current case indicates that increased ADC values within the splenic lesions suggest a vascular etiology, which might help narrow the differential diagnosis.

Original languageEnglish (US)
Pages (from-to)1105-1109
Number of pages5
JournalPediatric Radiology
Issue number10
Publication statusPublished - Oct 2009



  • ADC
  • Child
  • Diffusion-weighted imaging
  • Littoral cell angioma
  • Spleen

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Pediatrics, Perinatology, and Child Health

Cite this