Pediatric Limb Reconstruction in Osteogenesis Imperfecta

Steven L. Frick, Paul David Sponseller, Arabella Leet

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The indications for limb reconstruction surgery in children with osteogenesis imperfecta (OI) are recurrent long bone fractures or long bone deformity that interferes with function. Intramedullary rod fixation is the preferred method of stabilization, as it is load sharing and will splint the pathologic bone to reduce the incidence of fracture, progressive deformity and associated pain. Telescoping rod systems have been developed that will expand with growth and diminish the number of procedures necessary to keep the bone splinted during skeletal growth. Even with modern treatment consisting of medical management with bisphosphonates and surgical reconstruction with telescoping rods, reoperation is common. Children with OI have a higher incidence of non-union, which may be further increased by bisphosphonate therapy. Combined medical and surgical treatment lowers bone pain, fracture occurrence and can improve function.

Original languageEnglish (US)
Title of host publicationOsteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease
PublisherElsevier Inc.
Pages443-451
Number of pages9
ISBN (Print)9780123971654
DOIs
StatePublished - Sep 2013

Fingerprint

Osteogenesis Imperfecta
Telescopes
Extremities
Bone Fractures
Diphosphonates
Pediatrics
Bone and Bones
Pain
Splints
Incidence
Growth
Reoperation
Therapeutics

Keywords

  • Limb deformity
  • Non-union
  • Osteotomy
  • Telescoping intramedullary rods

ASJC Scopus subject areas

  • Medicine(all)
  • Dentistry(all)

Cite this

Frick, S. L., Sponseller, P. D., & Leet, A. (2013). Pediatric Limb Reconstruction in Osteogenesis Imperfecta. In Osteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease (pp. 443-451). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-397165-4.00047-2

Pediatric Limb Reconstruction in Osteogenesis Imperfecta. / Frick, Steven L.; Sponseller, Paul David; Leet, Arabella.

Osteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease. Elsevier Inc., 2013. p. 443-451.

Research output: Chapter in Book/Report/Conference proceedingChapter

Frick, SL, Sponseller, PD & Leet, A 2013, Pediatric Limb Reconstruction in Osteogenesis Imperfecta. in Osteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease. Elsevier Inc., pp. 443-451. https://doi.org/10.1016/B978-0-12-397165-4.00047-2
Frick SL, Sponseller PD, Leet A. Pediatric Limb Reconstruction in Osteogenesis Imperfecta. In Osteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease. Elsevier Inc. 2013. p. 443-451 https://doi.org/10.1016/B978-0-12-397165-4.00047-2
Frick, Steven L. ; Sponseller, Paul David ; Leet, Arabella. / Pediatric Limb Reconstruction in Osteogenesis Imperfecta. Osteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease. Elsevier Inc., 2013. pp. 443-451
@inbook{50a563bef8c844d39037c048fe46de9c,
title = "Pediatric Limb Reconstruction in Osteogenesis Imperfecta",
abstract = "The indications for limb reconstruction surgery in children with osteogenesis imperfecta (OI) are recurrent long bone fractures or long bone deformity that interferes with function. Intramedullary rod fixation is the preferred method of stabilization, as it is load sharing and will splint the pathologic bone to reduce the incidence of fracture, progressive deformity and associated pain. Telescoping rod systems have been developed that will expand with growth and diminish the number of procedures necessary to keep the bone splinted during skeletal growth. Even with modern treatment consisting of medical management with bisphosphonates and surgical reconstruction with telescoping rods, reoperation is common. Children with OI have a higher incidence of non-union, which may be further increased by bisphosphonate therapy. Combined medical and surgical treatment lowers bone pain, fracture occurrence and can improve function.",
keywords = "Limb deformity, Non-union, Osteotomy, Telescoping intramedullary rods",
author = "Frick, {Steven L.} and Sponseller, {Paul David} and Arabella Leet",
year = "2013",
month = "9",
doi = "10.1016/B978-0-12-397165-4.00047-2",
language = "English (US)",
isbn = "9780123971654",
pages = "443--451",
booktitle = "Osteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease",
publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Pediatric Limb Reconstruction in Osteogenesis Imperfecta

AU - Frick, Steven L.

AU - Sponseller, Paul David

AU - Leet, Arabella

PY - 2013/9

Y1 - 2013/9

N2 - The indications for limb reconstruction surgery in children with osteogenesis imperfecta (OI) are recurrent long bone fractures or long bone deformity that interferes with function. Intramedullary rod fixation is the preferred method of stabilization, as it is load sharing and will splint the pathologic bone to reduce the incidence of fracture, progressive deformity and associated pain. Telescoping rod systems have been developed that will expand with growth and diminish the number of procedures necessary to keep the bone splinted during skeletal growth. Even with modern treatment consisting of medical management with bisphosphonates and surgical reconstruction with telescoping rods, reoperation is common. Children with OI have a higher incidence of non-union, which may be further increased by bisphosphonate therapy. Combined medical and surgical treatment lowers bone pain, fracture occurrence and can improve function.

AB - The indications for limb reconstruction surgery in children with osteogenesis imperfecta (OI) are recurrent long bone fractures or long bone deformity that interferes with function. Intramedullary rod fixation is the preferred method of stabilization, as it is load sharing and will splint the pathologic bone to reduce the incidence of fracture, progressive deformity and associated pain. Telescoping rod systems have been developed that will expand with growth and diminish the number of procedures necessary to keep the bone splinted during skeletal growth. Even with modern treatment consisting of medical management with bisphosphonates and surgical reconstruction with telescoping rods, reoperation is common. Children with OI have a higher incidence of non-union, which may be further increased by bisphosphonate therapy. Combined medical and surgical treatment lowers bone pain, fracture occurrence and can improve function.

KW - Limb deformity

KW - Non-union

KW - Osteotomy

KW - Telescoping intramedullary rods

UR - http://www.scopus.com/inward/record.url?scp=84902430249&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902430249&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-397165-4.00047-2

DO - 10.1016/B978-0-12-397165-4.00047-2

M3 - Chapter

AN - SCOPUS:84902430249

SN - 9780123971654

SP - 443

EP - 451

BT - Osteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease

PB - Elsevier Inc.

ER -