Pediatric Limb Reconstruction in Osteogenesis Imperfecta

Steven L. Frick, Paul Sponseller, Arabella Leet

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The indications for limb reconstruction surgery in children with osteogenesis imperfecta (OI) are recurrent long bone fractures or long bone deformity that interferes with function. Intramedullary rod fixation is the preferred method of stabilization, as it is load sharing and will splint the pathologic bone to reduce the incidence of fracture, progressive deformity and associated pain. Telescoping rod systems have been developed that will expand with growth and diminish the number of procedures necessary to keep the bone splinted during skeletal growth. Even with modern treatment consisting of medical management with bisphosphonates and surgical reconstruction with telescoping rods, reoperation is common. Children with OI have a higher incidence of non-union, which may be further increased by bisphosphonate therapy. Combined medical and surgical treatment lowers bone pain, fracture occurrence and can improve function.

Original languageEnglish (US)
Title of host publicationOsteogenesis Imperfecta
Subtitle of host publicationA Translational Approach to Brittle Bone Disease
PublisherElsevier Inc.
Pages443-451
Number of pages9
ISBN (Print)9780123971654
DOIs
StatePublished - Sep 1 2013

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Keywords

  • Limb deformity
  • Non-union
  • Osteotomy
  • Telescoping intramedullary rods

ASJC Scopus subject areas

  • Medicine(all)
  • Dentistry(all)

Cite this

Frick, S. L., Sponseller, P., & Leet, A. (2013). Pediatric Limb Reconstruction in Osteogenesis Imperfecta. In Osteogenesis Imperfecta: A Translational Approach to Brittle Bone Disease (pp. 443-451). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-397165-4.00047-2