Pediatric decision-making: Informed consent, parental permission, and child assent

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Case narrative Osteosarcoma is a highly malignant bone cancer with a predilection for spreading to the lungs that primarily affects adolescents. Non-metastatic osteosarcoma has an approximate cure rate of 70%. Patients with osteosarcoma and metastases at the time of diagnosis are cured less than 20% of the time. Treatment consists of surgery and chemotherapy. Many children with cancer are treated according to clinical research trials. Michael, a 15-year-old with metastatic osteosarcoma, has not responded to conventional therapy. For almost one year, he was treated on a therapeutic randomized clinical trial, which consisted of standard therapy (up-front chemotherapy, limb salvage surgery, and postsurgical chemotherapy). When his cancer responded poorly to up-front therapy he was randomized to receive additional “experimental” chemotherapy.

Original languageEnglish (US)
Title of host publicationClinical Ethics in Pediatrics: A Case-Based Textbook
PublisherCambridge University Press
Pages1-6
Number of pages6
ISBN (Electronic)9780511740336
ISBN (Print)9780521173612
DOIs
StatePublished - Jan 1 2011

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Informed Consent
Osteosarcoma
Decision Making
Pediatrics
Drug Therapy
Therapeutics
Bone Neoplasms
Limb Salvage
Neoplasms
Randomized Controlled Trials
Clinical Trials
Neoplasm Metastasis
Lung
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Unguru, Y. (2011). Pediatric decision-making: Informed consent, parental permission, and child assent. In Clinical Ethics in Pediatrics: A Case-Based Textbook (pp. 1-6). Cambridge University Press. https://doi.org/10.1017/CBO9780511740336.002

Pediatric decision-making : Informed consent, parental permission, and child assent. / Unguru, Yoram.

Clinical Ethics in Pediatrics: A Case-Based Textbook. Cambridge University Press, 2011. p. 1-6.

Research output: Chapter in Book/Report/Conference proceedingChapter

Unguru, Y 2011, Pediatric decision-making: Informed consent, parental permission, and child assent. in Clinical Ethics in Pediatrics: A Case-Based Textbook. Cambridge University Press, pp. 1-6. https://doi.org/10.1017/CBO9780511740336.002
Unguru Y. Pediatric decision-making: Informed consent, parental permission, and child assent. In Clinical Ethics in Pediatrics: A Case-Based Textbook. Cambridge University Press. 2011. p. 1-6 https://doi.org/10.1017/CBO9780511740336.002
Unguru, Yoram. / Pediatric decision-making : Informed consent, parental permission, and child assent. Clinical Ethics in Pediatrics: A Case-Based Textbook. Cambridge University Press, 2011. pp. 1-6
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