Pediatric Acute Respiratory Distress Syndrome

Consensus Recommendations from the Pediatric Acute Lung Injury Consensus Conference

The Pediatric Acute Lung Injury Consensus Conference Group

Research output: Contribution to journalArticle

Abstract

Objective: To describe the final recommendations of the Pediatric Acute Lung Injury Consensus Conference. Design: Consensus conference of experts in pediatric acute lung injury. Setting: Not applicable. Subjects: PICU patients with evidence of acute lung injury or acute respiratory distress syndrome. Interventions: None. Methods: A panel of 27 experts met over the course of 2 years to develop a taxonomy to define pediatric acute respiratory distress syndrome and to make recommendations regarding treatment and research priorities. When published, data were lacking a modified Delphi approach emphasizing strong professional agreement was used. Measurements and Main Results: A panel of 27 experts met over the course of 2 years to develop a taxonomy to define pediatric acute respiratory distress syndrome and to make recommendations regarding treatment and research priorities. When published data were lacking a modified Delphi approach emphasizing strong professional agreement was used. The Pediatric Acute Lung Injury Consensus Conference experts developed and voted on a total of 151 recommendations addressing the following topics related to pediatric acute respiratory distress syndrome: 1) Definition, prevalence, and epidemiology; 2) Pathophysiology, comorbidities, and severity; 3) Ventilatory support; 4) Pulmonary-specific ancillary treatment; 5) Nonpulmonary treatment; 6) Monitoring; 7) Noninvasive support and ventilation; 8) Extracorporeal support; and 9) Morbidity and long-term outcomes. There were 132 recommendations with strong agreement and 19 recommendations with weak agreement. Once restated, the final iteration of the recommendations had none with equipoise or disagreement. Conclusions: The Consensus Conference developed pediatric-specific definitions for acute respiratory distress syndrome and recommendations regarding treatment and future research priorities. These are intended to promote optimization and consistency of care for children with pediatric acute respiratory distress syndrome and identify areas of uncertainty requiring further investigation.

Original languageEnglish (US)
Pages (from-to)428-439
Number of pages12
JournalPediatric Critical Care Medicine
Volume16
Issue number5
DOIs
StatePublished - Jun 21 2015

Fingerprint

Acute Lung Injury
Adult Respiratory Distress Syndrome
Pediatrics
Research
Therapeutics
Noninvasive Ventilation
Child Care
Uncertainty
Comorbidity
Epidemiology
Morbidity
Lung

Keywords

  • acute lung injury
  • acute respiratory distress syndrome
  • consensus development conference
  • guidelines
  • pediatrics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Critical Care and Intensive Care Medicine

Cite this

Pediatric Acute Respiratory Distress Syndrome : Consensus Recommendations from the Pediatric Acute Lung Injury Consensus Conference. / The Pediatric Acute Lung Injury Consensus Conference Group.

In: Pediatric Critical Care Medicine, Vol. 16, No. 5, 21.06.2015, p. 428-439.

Research output: Contribution to journalArticle

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abstract = "Objective: To describe the final recommendations of the Pediatric Acute Lung Injury Consensus Conference. Design: Consensus conference of experts in pediatric acute lung injury. Setting: Not applicable. Subjects: PICU patients with evidence of acute lung injury or acute respiratory distress syndrome. Interventions: None. Methods: A panel of 27 experts met over the course of 2 years to develop a taxonomy to define pediatric acute respiratory distress syndrome and to make recommendations regarding treatment and research priorities. When published, data were lacking a modified Delphi approach emphasizing strong professional agreement was used. Measurements and Main Results: A panel of 27 experts met over the course of 2 years to develop a taxonomy to define pediatric acute respiratory distress syndrome and to make recommendations regarding treatment and research priorities. When published data were lacking a modified Delphi approach emphasizing strong professional agreement was used. The Pediatric Acute Lung Injury Consensus Conference experts developed and voted on a total of 151 recommendations addressing the following topics related to pediatric acute respiratory distress syndrome: 1) Definition, prevalence, and epidemiology; 2) Pathophysiology, comorbidities, and severity; 3) Ventilatory support; 4) Pulmonary-specific ancillary treatment; 5) Nonpulmonary treatment; 6) Monitoring; 7) Noninvasive support and ventilation; 8) Extracorporeal support; and 9) Morbidity and long-term outcomes. There were 132 recommendations with strong agreement and 19 recommendations with weak agreement. Once restated, the final iteration of the recommendations had none with equipoise or disagreement. Conclusions: The Consensus Conference developed pediatric-specific definitions for acute respiratory distress syndrome and recommendations regarding treatment and future research priorities. These are intended to promote optimization and consistency of care for children with pediatric acute respiratory distress syndrome and identify areas of uncertainty requiring further investigation.",
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author = "{The Pediatric Acute Lung Injury Consensus Conference Group} and Philippe Jouvet and Thomas, {Neal J.} and Willson, {Douglas F.} and Simon Erickson and Robinder Khemani and Lincoln Smith and Jerry Zimmerman and Mary Dahmer and Heidi Flori and Michael Quasney and Anil Sapru and Ira Cheifetz and Rimensberger, {Peter C.} and Martin Kneyber and Tamburro, {Robert F.} and Curley, {Martha A.Q.} and Vinay Nadkarni and Stacey Valentine and Guillaume Emeriaud and Christopher Newth and Carroll, {Christopher L.} and Sandrine Essouri and Heidi Dalton and Duncan Macrae and Yolanda Lopez-Cruces and Miriam Santschi and {Scott Watson}, R. and Melania Bembea",
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