Patterns of Uveitis in a Tertiary Care Referral Institute in Saudi Arabia

Hassan A. Al Dhibi, Hanan N. Al Shamsi, Ammar M. Al-Mahmood, Hassan M. Al Taweel, Mohammed A. Al Shamrani, J Fernando Arevalo, Vishali Gupta, KKESH Uveitis Survey Study Group The KKESH Uveitis Survey Study Group

Research output: Contribution to journalArticle

Abstract

Purpose: To present the pattern, causes and complications of uveitis in one of the tertiary eye centers in Saudi Arabia. Methods: In this retrospective study, clinical records of randomly selected cases of uveitis attending the King Khaled Eye Specialist Hospital, Saudi Arabia, from 2001 to 2010, were reviewed. Results: Our series included 888 out of 1286 cases of uveitis. Among them, there were 390 men (43.9%) with a mean age of 39.6 ± 11 (range: 6–94 years). The prevalence of uveitis among all eye patients was 1.5% and the annual incidence was 129 cases. Uveitis was bilateral in 567 patients (63.8%), mainly anterior in 27.3%, intermediate in 12.7%, posterior in 7.1%, while 52.9% were panuveitis. Infective etiology was seen in 180 patients (20.3%), of which presumed tuberculous uveitis (PTU) was the commonest cause in 94 patients (52%), followed by herpetic in 46 (26%) and toxoplasmosis in 29 (16%). Vogt–Koyanagi–Harada (VKH) 22%, Behçet uveitis (BU) 14.6%, idiopathic anterior uveitis 12.5%, presumed tuberculous uveitis (PTU) 10.6%, and idiopathic intermediate uveitis (10.1%) accounted for the majority of cases, whereas other diagnostic entities accounted for 30%. The most common cause of anterior uveitis was idiopathic uveitis (101; 41.7%), followed by herpetic (46; 19%). Toxoplasmosis was the most frequent cause of posterior uveitis (29; 46.3%). Intermediate uveitis was most commonly idiopathic (86; 76.1%). VKH disease was the most common cause of panuveitis (195; 41.5%), followed by Behçet disease (118; 25.1%). The common complications of uveitis were glaucoma (34.1%), posterior synechiae (22.3%) and cataract (15.1%). Conclusions: The most common anatomic diagnosis was panuveitis. VKH disease and Behçet disease were the most frequent causes and glaucoma was the most common complication of uveitis.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalOcular Immunology and Inflammation
DOIs
StateAccepted/In press - Feb 26 2016

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Saudi Arabia
Uveitis
Tertiary Healthcare
Referral and Consultation
Panuveitis
Intermediate Uveitis
Anterior Uveitis
Toxoplasmosis
Glaucoma
Posterior Uveitis
Cataract
Retrospective Studies

Keywords

  • Behçet disease
  • epidemiology
  • Saudi Arabia
  • uveitis
  • VKH disease

ASJC Scopus subject areas

  • Ophthalmology
  • Immunology and Allergy

Cite this

Al Dhibi, H. A., Al Shamsi, H. N., Al-Mahmood, A. M., Al Taweel, H. M., Al Shamrani, M. A., Arevalo, J. F., ... The KKESH Uveitis Survey Study Group, KKESH. U. S. S. G. (Accepted/In press). Patterns of Uveitis in a Tertiary Care Referral Institute in Saudi Arabia. Ocular Immunology and Inflammation, 1-8. https://doi.org/10.3109/09273948.2015.1133836

Patterns of Uveitis in a Tertiary Care Referral Institute in Saudi Arabia. / Al Dhibi, Hassan A.; Al Shamsi, Hanan N.; Al-Mahmood, Ammar M.; Al Taweel, Hassan M.; Al Shamrani, Mohammed A.; Arevalo, J Fernando; Gupta, Vishali; The KKESH Uveitis Survey Study Group, KKESH Uveitis Survey Study Group.

In: Ocular Immunology and Inflammation, 26.02.2016, p. 1-8.

Research output: Contribution to journalArticle

Al Dhibi, HA, Al Shamsi, HN, Al-Mahmood, AM, Al Taweel, HM, Al Shamrani, MA, Arevalo, JF, Gupta, V & The KKESH Uveitis Survey Study Group, KKESHUSSG 2016, 'Patterns of Uveitis in a Tertiary Care Referral Institute in Saudi Arabia', Ocular Immunology and Inflammation, pp. 1-8. https://doi.org/10.3109/09273948.2015.1133836
Al Dhibi, Hassan A. ; Al Shamsi, Hanan N. ; Al-Mahmood, Ammar M. ; Al Taweel, Hassan M. ; Al Shamrani, Mohammed A. ; Arevalo, J Fernando ; Gupta, Vishali ; The KKESH Uveitis Survey Study Group, KKESH Uveitis Survey Study Group. / Patterns of Uveitis in a Tertiary Care Referral Institute in Saudi Arabia. In: Ocular Immunology and Inflammation. 2016 ; pp. 1-8.
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abstract = "Purpose: To present the pattern, causes and complications of uveitis in one of the tertiary eye centers in Saudi Arabia. Methods: In this retrospective study, clinical records of randomly selected cases of uveitis attending the King Khaled Eye Specialist Hospital, Saudi Arabia, from 2001 to 2010, were reviewed. Results: Our series included 888 out of 1286 cases of uveitis. Among them, there were 390 men (43.9{\%}) with a mean age of 39.6 ± 11 (range: 6–94 years). The prevalence of uveitis among all eye patients was 1.5{\%} and the annual incidence was 129 cases. Uveitis was bilateral in 567 patients (63.8{\%}), mainly anterior in 27.3{\%}, intermediate in 12.7{\%}, posterior in 7.1{\%}, while 52.9{\%} were panuveitis. Infective etiology was seen in 180 patients (20.3{\%}), of which presumed tuberculous uveitis (PTU) was the commonest cause in 94 patients (52{\%}), followed by herpetic in 46 (26{\%}) and toxoplasmosis in 29 (16{\%}). Vogt–Koyanagi–Harada (VKH) 22{\%}, Beh{\cc}et uveitis (BU) 14.6{\%}, idiopathic anterior uveitis 12.5{\%}, presumed tuberculous uveitis (PTU) 10.6{\%}, and idiopathic intermediate uveitis (10.1{\%}) accounted for the majority of cases, whereas other diagnostic entities accounted for 30{\%}. The most common cause of anterior uveitis was idiopathic uveitis (101; 41.7{\%}), followed by herpetic (46; 19{\%}). Toxoplasmosis was the most frequent cause of posterior uveitis (29; 46.3{\%}). Intermediate uveitis was most commonly idiopathic (86; 76.1{\%}). VKH disease was the most common cause of panuveitis (195; 41.5{\%}), followed by Beh{\cc}et disease (118; 25.1{\%}). The common complications of uveitis were glaucoma (34.1{\%}), posterior synechiae (22.3{\%}) and cataract (15.1{\%}). Conclusions: The most common anatomic diagnosis was panuveitis. VKH disease and Beh{\cc}et disease were the most frequent causes and glaucoma was the most common complication of uveitis.",
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AU - Al Taweel, Hassan M.

AU - Al Shamrani, Mohammed A.

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N2 - Purpose: To present the pattern, causes and complications of uveitis in one of the tertiary eye centers in Saudi Arabia. Methods: In this retrospective study, clinical records of randomly selected cases of uveitis attending the King Khaled Eye Specialist Hospital, Saudi Arabia, from 2001 to 2010, were reviewed. Results: Our series included 888 out of 1286 cases of uveitis. Among them, there were 390 men (43.9%) with a mean age of 39.6 ± 11 (range: 6–94 years). The prevalence of uveitis among all eye patients was 1.5% and the annual incidence was 129 cases. Uveitis was bilateral in 567 patients (63.8%), mainly anterior in 27.3%, intermediate in 12.7%, posterior in 7.1%, while 52.9% were panuveitis. Infective etiology was seen in 180 patients (20.3%), of which presumed tuberculous uveitis (PTU) was the commonest cause in 94 patients (52%), followed by herpetic in 46 (26%) and toxoplasmosis in 29 (16%). Vogt–Koyanagi–Harada (VKH) 22%, Behçet uveitis (BU) 14.6%, idiopathic anterior uveitis 12.5%, presumed tuberculous uveitis (PTU) 10.6%, and idiopathic intermediate uveitis (10.1%) accounted for the majority of cases, whereas other diagnostic entities accounted for 30%. The most common cause of anterior uveitis was idiopathic uveitis (101; 41.7%), followed by herpetic (46; 19%). Toxoplasmosis was the most frequent cause of posterior uveitis (29; 46.3%). Intermediate uveitis was most commonly idiopathic (86; 76.1%). VKH disease was the most common cause of panuveitis (195; 41.5%), followed by Behçet disease (118; 25.1%). The common complications of uveitis were glaucoma (34.1%), posterior synechiae (22.3%) and cataract (15.1%). Conclusions: The most common anatomic diagnosis was panuveitis. VKH disease and Behçet disease were the most frequent causes and glaucoma was the most common complication of uveitis.

AB - Purpose: To present the pattern, causes and complications of uveitis in one of the tertiary eye centers in Saudi Arabia. Methods: In this retrospective study, clinical records of randomly selected cases of uveitis attending the King Khaled Eye Specialist Hospital, Saudi Arabia, from 2001 to 2010, were reviewed. Results: Our series included 888 out of 1286 cases of uveitis. Among them, there were 390 men (43.9%) with a mean age of 39.6 ± 11 (range: 6–94 years). The prevalence of uveitis among all eye patients was 1.5% and the annual incidence was 129 cases. Uveitis was bilateral in 567 patients (63.8%), mainly anterior in 27.3%, intermediate in 12.7%, posterior in 7.1%, while 52.9% were panuveitis. Infective etiology was seen in 180 patients (20.3%), of which presumed tuberculous uveitis (PTU) was the commonest cause in 94 patients (52%), followed by herpetic in 46 (26%) and toxoplasmosis in 29 (16%). Vogt–Koyanagi–Harada (VKH) 22%, Behçet uveitis (BU) 14.6%, idiopathic anterior uveitis 12.5%, presumed tuberculous uveitis (PTU) 10.6%, and idiopathic intermediate uveitis (10.1%) accounted for the majority of cases, whereas other diagnostic entities accounted for 30%. The most common cause of anterior uveitis was idiopathic uveitis (101; 41.7%), followed by herpetic (46; 19%). Toxoplasmosis was the most frequent cause of posterior uveitis (29; 46.3%). Intermediate uveitis was most commonly idiopathic (86; 76.1%). VKH disease was the most common cause of panuveitis (195; 41.5%), followed by Behçet disease (118; 25.1%). The common complications of uveitis were glaucoma (34.1%), posterior synechiae (22.3%) and cataract (15.1%). Conclusions: The most common anatomic diagnosis was panuveitis. VKH disease and Behçet disease were the most frequent causes and glaucoma was the most common complication of uveitis.

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KW - epidemiology

KW - Saudi Arabia

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