TY - JOUR
T1 - Patterns of mortality among commercial pressmen
AU - Zoloth, Stephen R.
AU - Michaels, David M.
AU - Villalbi, Joan Ramon
AU - Lacher, Margot
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1986/6
Y1 - 1986/6
N2 - A proportionate analysis of cause of death in 1, 401 commercial pressmen was initiated following a report of a cancer cluster in this group. The study found a significant elevated risk of all cancers [proportionate mortality ratio (PMR)=127) and cancers of the lymphatic and hematopoietic system (PMR= 122), with non-Hodgkin's lymphomas responsible for much of the excess. Three deaths in the cohort were attributed to myelofibrosis, a rare disease associated with benzene exposure. A significantly elevated PMR was also detected for colorectal cancer (PMR=171) and, among those employed 20 years or more, for cancers of the liver (PMR=216) and pancreas (PMR=162). No excess risk of bladder or lung cancer or leukemia was seen. Proportionate mortality analyses rarely show excess risk of both cancer and heart disease in a working population. Surprisingly, a significantly elevated risk of arteriosclerotic heart disease (PMR=113) was found in this group. These findings indicate that solvent exposure may be associated with excess mortality risk in commercial pressmen.
AB - A proportionate analysis of cause of death in 1, 401 commercial pressmen was initiated following a report of a cancer cluster in this group. The study found a significant elevated risk of all cancers [proportionate mortality ratio (PMR)=127) and cancers of the lymphatic and hematopoietic system (PMR= 122), with non-Hodgkin's lymphomas responsible for much of the excess. Three deaths in the cohort were attributed to myelofibrosis, a rare disease associated with benzene exposure. A significantly elevated PMR was also detected for colorectal cancer (PMR=171) and, among those employed 20 years or more, for cancers of the liver (PMR=216) and pancreas (PMR=162). No excess risk of bladder or lung cancer or leukemia was seen. Proportionate mortality analyses rarely show excess risk of both cancer and heart disease in a working population. Surprisingly, a significantly elevated risk of arteriosclerotic heart disease (PMR=113) was found in this group. These findings indicate that solvent exposure may be associated with excess mortality risk in commercial pressmen.
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U2 - 10.1093/jnci/76.6.1047
DO - 10.1093/jnci/76.6.1047
M3 - Article
C2 - 3458942
AN - SCOPUS:0022591788
SN - 0027-8874
VL - 76
SP - 1047
EP - 1051
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
IS - 6
ER -