TY - JOUR
T1 - Patterns of gastric myoelectrical activity in human subjects of different ages
AU - Chen, J. D.Z.
AU - Co, E.
AU - Liang, J.
AU - Pan, J.
AU - Sutphen, J.
AU - Torres-Pinedo, R. B.
AU - Orr, W. C.
PY - 1997/5
Y1 - 1997/5
N2 - The aim of this study was to investigate the developmental change of gastric myoelectrical activity in humans. Five groups of healthy subjects were studied, including 10 preterm newborns, 8 full-term newborns, 8 full- term infants (ages 2-6 mo), 9 children (ages 4-11 yr), and 9 adults. Gastric myoelectrical activity was recorded using surface electrogastrography for 30 min before and 30 min after a test meal in each subject. Spectral analysis methods were applied to compute the parameters of the electrogastrogram (EGG). The results showed that the percentage of 2-to 4-cycles/min (cpm) slow waves was 26.6 ± 3.9% in the preterm newborns, 30.0 ± 4.0% in full-term newborns, 70 ± 6.1% in 2- to 6-mo-old infants (P < 0.001 compared with newborns), 84.6 ± 3.2% in 4- to 11-yr-old children (P < 0.03 compared with infants), and 88.9 ± 2.2% in the adults (P > 0.05 compared with children). In conclusion, gastric slow waves are absent at birth, and there is a maturing process after birth. Age-matched controls are necessary for the interpretation of EGG data from neonates and infants, whereas EGG data in children are the same as in adults.
AB - The aim of this study was to investigate the developmental change of gastric myoelectrical activity in humans. Five groups of healthy subjects were studied, including 10 preterm newborns, 8 full-term newborns, 8 full- term infants (ages 2-6 mo), 9 children (ages 4-11 yr), and 9 adults. Gastric myoelectrical activity was recorded using surface electrogastrography for 30 min before and 30 min after a test meal in each subject. Spectral analysis methods were applied to compute the parameters of the electrogastrogram (EGG). The results showed that the percentage of 2-to 4-cycles/min (cpm) slow waves was 26.6 ± 3.9% in the preterm newborns, 30.0 ± 4.0% in full-term newborns, 70 ± 6.1% in 2- to 6-mo-old infants (P < 0.001 compared with newborns), 84.6 ± 3.2% in 4- to 11-yr-old children (P < 0.03 compared with infants), and 88.9 ± 2.2% in the adults (P > 0.05 compared with children). In conclusion, gastric slow waves are absent at birth, and there is a maturing process after birth. Age-matched controls are necessary for the interpretation of EGG data from neonates and infants, whereas EGG data in children are the same as in adults.
KW - Development
KW - Electrogastrography
KW - Gastric motility
KW - Stomach
UR - http://www.scopus.com/inward/record.url?scp=0031008104&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031008104&partnerID=8YFLogxK
U2 - 10.1152/ajpgi.1997.272.5.g1022
DO - 10.1152/ajpgi.1997.272.5.g1022
M3 - Article
C2 - 9176209
AN - SCOPUS:0031008104
SN - 0193-1857
VL - 272
SP - G1022-G1027
JO - American Journal of Physiology - Gastrointestinal and Liver Physiology
JF - American Journal of Physiology - Gastrointestinal and Liver Physiology
IS - 5 35-5
ER -