Abstract
The clinical courses of 41 patients with ampullary carcinoma were retrospectively reviewed to determine patterns of failure after resection. The five year actuarial local control and overall survival rates of 29 patients undergoing only pancreaticoduodenectomy were 69 and 55 percent, respectively. For 12 patients with 'low risk' pathologic features (tumors limited to the ampulla or duodenum, well or moderately well-differentiated histologic factors, uninvolved lymph nodes or resection margins), the five year actuarial local control and survival rate was 100 and 80 percent, respectively. Adjuvant treatment may be unnecessary for this favorable subset of patients. On the other hand, the five year actuarial local control and survival after pancreaticoduodenectomy of 17 patients with 'high-risk' pathologic features (tumors invasive of the pancreas, poorly differentiated histologic findings, involved lymph nodes or resection margins) was only 50 and 38 percent, respectively (p
| Original language | English (US) |
|---|---|
| Pages (from-to) | 33-38 |
| Number of pages | 6 |
| Journal | Surgery Gynecology and Obstetrics |
| Volume | 176 |
| Issue number | 1 |
| State | Published - 1993 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Obstetrics and Gynecology
- Surgery
Cite this
Patterns of failure after pancreaticoduodenectomy for ampullary carcinoma. / Willett, C. G.; Warshaw, A. L.; Convery, K.; Compton, C. C.
In: Surgery Gynecology and Obstetrics, Vol. 176, No. 1, 1993, p. 33-38.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Patterns of failure after pancreaticoduodenectomy for ampullary carcinoma
AU - Willett, C. G.
AU - Warshaw, A. L.
AU - Convery, K.
AU - Compton, C. C.
PY - 1993
Y1 - 1993
N2 - The clinical courses of 41 patients with ampullary carcinoma were retrospectively reviewed to determine patterns of failure after resection. The five year actuarial local control and overall survival rates of 29 patients undergoing only pancreaticoduodenectomy were 69 and 55 percent, respectively. For 12 patients with 'low risk' pathologic features (tumors limited to the ampulla or duodenum, well or moderately well-differentiated histologic factors, uninvolved lymph nodes or resection margins), the five year actuarial local control and survival rate was 100 and 80 percent, respectively. Adjuvant treatment may be unnecessary for this favorable subset of patients. On the other hand, the five year actuarial local control and survival after pancreaticoduodenectomy of 17 patients with 'high-risk' pathologic features (tumors invasive of the pancreas, poorly differentiated histologic findings, involved lymph nodes or resection margins) was only 50 and 38 percent, respectively (p
AB - The clinical courses of 41 patients with ampullary carcinoma were retrospectively reviewed to determine patterns of failure after resection. The five year actuarial local control and overall survival rates of 29 patients undergoing only pancreaticoduodenectomy were 69 and 55 percent, respectively. For 12 patients with 'low risk' pathologic features (tumors limited to the ampulla or duodenum, well or moderately well-differentiated histologic factors, uninvolved lymph nodes or resection margins), the five year actuarial local control and survival rate was 100 and 80 percent, respectively. Adjuvant treatment may be unnecessary for this favorable subset of patients. On the other hand, the five year actuarial local control and survival after pancreaticoduodenectomy of 17 patients with 'high-risk' pathologic features (tumors invasive of the pancreas, poorly differentiated histologic findings, involved lymph nodes or resection margins) was only 50 and 38 percent, respectively (p
UR - http://www.scopus.com/inward/record.url?scp=0027530491&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027530491&partnerID=8YFLogxK
M3 - Article
C2 - 8093983
AN - SCOPUS:0027530491
VL - 176
SP - 33
EP - 38
JO - Journal of the American College of Surgeons
JF - Journal of the American College of Surgeons
SN - 1072-7515
IS - 1
ER -