Patterns of anaphylaxis: Acute and late phase features of allergic reactions

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Anaphylaxis is usually defined as a multi-system allergic reaction, but includes isolated shock or airway obstruction. Hives do not occur in 20-30% of cases. Gastrointestinal (GI) symptoms are more common with foods. Cardiac anaphylaxis can cause arrhythmias, bradycardia or chest pain with ECG changes. Plasma histamine level correlates with hives and GI symptoms. Serum tryptase is elevated less often in food allergy, and correlates poorly with plasma histamine level. Anaphylaxis occurs in 30/100 000 population/year (mortality 1-2%) and is caused by foods (35%), drugs/biologicals (25%), insect stings (15%), exercise (5%) or is idiopathic (20%). Onset of anaphylaxis to stings or allergen injections is usually rapid: 70% begin in

Original languageEnglish (US)
Title of host publicationNovartis Foundation Symposium
Pages101-110
Number of pages10
Volume257
StatePublished - 2004

Publication series

NameNovartis Foundation Symposium
Volume257
ISSN (Print)15282511

Fingerprint

Anaphylaxis
Hypersensitivity
Urticaria
Histamine
Insect Bites and Stings
Tryptases
Food
Food Hypersensitivity
Airway Obstruction
Bites and Stings
Bradycardia
Chest Pain
Allergens
Cardiac Arrhythmias
Shock
Electrocardiography
Injections
Mortality
Serum
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Golden, D. B. K. (2004). Patterns of anaphylaxis: Acute and late phase features of allergic reactions. In Novartis Foundation Symposium (Vol. 257, pp. 101-110). (Novartis Foundation Symposium; Vol. 257).

Patterns of anaphylaxis : Acute and late phase features of allergic reactions. / Golden, David B K.

Novartis Foundation Symposium. Vol. 257 2004. p. 101-110 (Novartis Foundation Symposium; Vol. 257).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Golden, DBK 2004, Patterns of anaphylaxis: Acute and late phase features of allergic reactions. in Novartis Foundation Symposium. vol. 257, Novartis Foundation Symposium, vol. 257, pp. 101-110.
Golden DBK. Patterns of anaphylaxis: Acute and late phase features of allergic reactions. In Novartis Foundation Symposium. Vol. 257. 2004. p. 101-110. (Novartis Foundation Symposium).
Golden, David B K. / Patterns of anaphylaxis : Acute and late phase features of allergic reactions. Novartis Foundation Symposium. Vol. 257 2004. pp. 101-110 (Novartis Foundation Symposium).
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